Biochemistry PhD Projects, Programmes & Scholarships

Design and Evolution of Enzymes with New Catalytic Functions

The University of Manchester Department of Chemistry

A fully funded studentship is available, based at the Manchester Institute of Biotechnology under the supervision of Prof Anthony Green. Read more

Supervisor: Prof A Green

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Building Enzymes with New Catalytic Functions & Design and Evolution of Enzymes with New Catalytic Functions

The University of Manchester Department of Chemistry

A fully funded studentship is available, based at the Manchester Institute of Biotechnology under the supervision of Prof Anthony Green. Read more

Supervisor: Prof A Green

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

The University of Manchester Department of Chemistry

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

Supervisors: Dr S Lovelock, Dr C Markin

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Sustainable Commodity Chemicals through Enzyme Engineering & Design (SuCCEED) - 4 posts available

The University of Manchester Department of Chemistry

SuCCEED is a BBSRC-funded Prosperity Partnership multi-million project between The University of Manchester and Shell. Commodity chemicals are produced on a global scale and normally derived from finite geological sources. Read more

Supervisors: Dr N Dixon, Dr J Esteban Serrano, Prof A Green, Prof D Leys, Dr V Spallina, Prof M Turner, Dr J Winterburn

30 June 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

The University of Manchester Department of Chemistry

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

Supervisor: Dr C Megarity

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

The University of Manchester Department of Chemistry

Ecteinascidin 743 (ET-743, Trabectedin) is a marine-derived natural organic compound approved for the treatment of soft tissue sarcomas. Read more

Supervisors: Prof E Takano, Prof H Oguri

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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New Methods for modelling cofactor-dependent enzyme structure and function

The University of Manchester Department of Chemistry

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Supervisor: Prof S Hay

27 October 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Characterising human sebum using NMR approaches

The University of Manchester Department of Chemistry

We have recently shown that skin secretions in particular sebum, has a critical diagnostic role in other diseases unrelated directly to the skin. Read more

Supervisors: Dr D K Trivedi, Prof M Nilsson, Prof GA Morris

Year round applications PhD Research Project Self-Funded PhD Students Only

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Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

The University of Manchester Department of Chemistry

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

Supervisor: Dr L Wong

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering Ice-Binding Proteins

The University of Manchester Department of Chemistry

Ice-binding proteins are produced by extremophiles to help them survive in the worlds coldest places. They have many potential applications, from the storage of cells/tissue to transport infrastructure. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Self-Funded PhD Students Only

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High-throughput biomaterials discovery

The University of Manchester Department of Chemistry

Polymer biomaterials have revolutionised a range of areas from drug delivery, to antimicrobials, to cellular cryopreservation. There are 1000’s of possible monomer combinations, molecular weights and architectures to be explored, and even small differences can dramatically change their properties. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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New strategies to cryopreserve cell-based therapies

The University of Manchester Department of Chemistry

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

The University of Manchester Department of Chemistry

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Supervisors: Dr A Bowen, Dr J Rowbotham, Dr I Riddell, Dr D Heyes

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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NMR approaches for understanding mass transfer in microbial biofilms and sessile microbial communities

The University of Manchester Department of Chemistry

Biofilms are structured sessile communities of microorganisms with relevance in many areas of life. They are almost omnipresent in aquatic and terrestrial ecosystems. Read more

Supervisors: Prof M Nilsson, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 14 Biochemistry PhD Projects, Programmes & Scholarships

Biochemistry PhD Projects, Programmes & Scholarships

We have 14 Biochemistry PhD Projects, Programmes & Scholarships

Design and Evolution of Enzymes with New Catalytic Functions

Building Enzymes with New Catalytic Functions & Design and Evolution of Enzymes with New Catalytic Functions

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

Sustainable Commodity Chemicals through Enzyme Engineering & Design (SuCCEED) - 4 posts available

Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

(University of Manchester - University of Tokyo Dual Award) Diversifying Antitumor Drugs through the Integration of Synthetic Biology and Chemo-enzymatic Approaches

New Methods for modelling cofactor-dependent enzyme structure and function

Characterising human sebum using NMR approaches

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

Engineering Ice-Binding Proteins

High-throughput biomaterials discovery

New strategies to cryopreserve cell-based therapies

Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

NMR approaches for understanding mass transfer in microbial biofilms and sessile microbial communities

We have 14 Biochemistry PhD Projects, Programmes & Scholarships

Biochemistry PhD Projects, Programmes & Scholarships

We have 14 Biochemistry PhD Projects, Programmes & Scholarships

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