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Biochemistry (action research) PhD Projects, Programs & Scholarships

We have 64 Biochemistry (action research) PhD Projects, Programs & Scholarships

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  Targeting ageing: Genes and compounds with pro-longevity, health-preserving effects
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

Ageing is arguably the major biomedical challenge of the 21st century. In model organisms, the process of ageing can be manipulated by both genetic manipulations and dietary interventions.
  Adjuvant therapies for mupirocin-resistant bacteria
  Dr B Bonev, Dr A Cockayne
Applications accepted all year round

Funding Type

PhD Type

Multi-drug resistant Staphylococcus aureus has been able to adapt constantly to therapeutic use of antibiotics and remains an important source of clinical complications, morbidity and mortality.
  Inhibitors of cilia and Hedgehog signaling: from phenotype to mechanistic understanding
  Prof S Hoogendoorn
Applications accepted all year round

Funding Type

PhD Type

The Hedgehog (Hh) signaling pathway is a major contributor to embryonic development, and tissue homeostasis and stem cell maintenance in children and adults.
  MRC DiMeN Doctoral Training Partnership: Understanding zinc-dependent regulation of TRPC5 channels and its role in diabetes
  Dr R.S. Bon, Dr S Muench, Dr P Sukumar
Application Deadline: 6 January 2020

Funding Type

PhD Type

TRPC5 ion channels are emerging drug targets, for example for CNS disorders, renal disease, cancer and cardiovascular disease (Cells 2018, 7, pii.
  MRC DiMeN Doctoral Training Partnership: From Live Cells to Single-molecules: Unravelling the interplay between 3D genomic structure and gene expression
  Dr C Toseland, Dr T Craggs
Application Deadline: 6 January 2020

Funding Type

PhD Type

This studentship is focused on applying state-of-the-art single molecule imaging techniques to study the molecular basis of DNA condensation and its impact upon gene expression.
  MRC DiMeN Doctoral Training Partnership: From Live Cells to Single-molecules: Unravelling the interplay between 3D genomic structure and gene expression
  Dr C Toseland, Dr T Craggs
Application Deadline: 6 January 2020

Funding Type

PhD Type

This studentship is focused on applying state-of-the-art single molecule imaging techniques to study the molecular basis of DNA condensation and its impact upon gene expression.
  (BBSRC DTP) A computational model for improving catalytic rate in enzymes
  Dr J Warwicker, Dr S De Visser, Dr S Hay
Application Deadline: 31 January 2020

Funding Type

PhD Type

Directed evolution of enzyme activity is an established methodology, generating biocatalysts that are of benefit for biotechnology, for example in bioenergy production [Turner 2009].
  Disrupting the regulatory mechanisms that allow hospital acquired infections to resist antibiotic therapy.
  Dr R McCarthy
Applications accepted all year round

Funding Type

PhD Type

The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare systems around the world revolutionised global health and wellbeing.
  Investigating the role of bioactive lipids in skin health
  Prof A Nicolaou, Prof C A O'Neill
Applications accepted all year round

Funding Type

PhD Type

Human skin depends on systemic provision of fatty acids that are important to maintain the integrity of the epidermal barrier as well as to support the associated immune and inflammatory reactions.
  The mechanism of regulation of protein synthesis via eIF2 molecular complexes
  Dr A Roseman, Prof G D Pavitt
Applications accepted all year round

Funding Type

PhD Type

Control of protein synthesis is critical for normal metabolism, development and responses to stress. One major pathway is called the integrated stress response (ISR) and centres on translational control of the general protein synthesis factor eIF2B via the phosphorylation of eIF2 [1,2].
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