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We have 9 Biochemistry (alternative medicine) PhD Projects, Programmes & Scholarships

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Biochemistry (alternative medicine) PhD Projects, Programmes & Scholarships

We have 9 Biochemistry (alternative medicine) PhD Projects, Programmes & Scholarships

The effect of early-life stress on cardiac function in later life

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Targeting the extracellular matrix remodelling for the treatment of obesity-associated cardio-renal dysfunction

Obesity is a risk factor for many chronic metabolic diseases including heart failure and chronic kidney disease. Our lab demonstrated a tight association between increased deposition of extracellular matrix components (e.g. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more
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Investigation of novel glycoconjugate vaccines to produce mucosal and systemic immunity against Group A Streptococcus.

Glycoconjugate vaccines have shown to be effective for several mucosal pathogens such as Streptococcus pneumoniae. While there is still no licensed vaccine against Group A Streptococcus (GAS), there has been significant progress in the development of candidate vaccines in recent years. Read more

Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development. Read more
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