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Biochemistry (cell therapy) PhD Projects, Programs & Scholarships

We have 41 Biochemistry (cell therapy) PhD Projects, Programs & Scholarships

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We have 41 Biochemistry (cell therapy) PhD Projects, Programs & Scholarships

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Macrophage driven therapy resistance in AML: from macrophage subset characterisation to therapeutic targeting.

  Research Group: Molecular Mechanisms and Long Term Conditions
Reference. SHLS20065. Background. Acute Myeloid Leukaemia (AML) is a common blood cancer in adults; with its incidence increasing with age, AML cases are predicted to double by 2030. Read more

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

MRC DiMeN Doctoral Training Partnership: Elucidating a structural basis for pathogenic mutations in B cell lymphoma

Cancer is a major health problem worldwide and it is believed that 1 in 2 people will develop a form of cancer in their lifetime. Despite recent progress in our understanding of cancer cell biology, current treatments are only effective for some patients. Read more

Nanoparticle synthesis and application in magnetic field hyperthermia for cancer therapy

  Research Group: Chemistry and Biosciences
Magnetic field hyperthermia (MFH) is currently undergoing clinical trials for use in humans. The research to date has shown the effectiveness of the approach in cells and animal models and the initial results from human trials are promising. Read more

(BBSRC DTP) Hormonal regulation of mast cell activity

Oestrogen levels fluctuate throughout life, impacting tissue function during menses, pregnancy and menopause. Oestrogen greatly affects immune responses, often enhancing the activities of both the innate and adaptive immune system. Read more

Intracrine GPCRs as master regulators of adipocyte lipolysis and metabolic disease

This project, funded through the MRC Advanced Inter-disciplinary Models Doctoral Training Partnership (AIM DTP), aims at investigating a new emerging paradigm in G protein-coupled receptor (GPCR) signalling in the control of adipocyte metabolism and its implications for the pharmacological therapy of metabolic disease. Read more

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