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Biochemistry (death) PhD Projects, Programs & Scholarships

We have 70 Biochemistry (death) PhD Projects, Programs & Scholarships

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  PhD in Earth Sciences: Is coral bleaching getting fatter?
  Dr N Kamenos, Prof J Toney, Dr D Exton, Dr H Burdett
Application Deadline: 10 January 2020

Funding Type

PhD Type

The ecosystem services provided by coral reefs are worth over $100 billion annually and include coast line protection, tourism, food and medical derivatives.
  Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round

Funding Type

PhD Type

Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine.
  Nanoinjection: a single molecule platform for the quantitative and targeted delivery of proteins into cells for functional analysis
  Research Group: BBSRC White Rose DTP
  Dr E W Hewitt, Dr P Actis, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

Interested in amyloid disorders such as Parkinson’s and Huntington’s. Want to work with cutting edge technology in a multidisciplinary team.
  Understanding amyloid aggregation mechanisms of alpha- and gamma synuclein in vitro and in vivo
  Research Group: BBSRC White Rose DTP
  Dr P van Oosten-Hawle, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

A key pathological hallmark of synucleopathies, including Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS), is the formation of cytotoxic alpha-synuclein and gamma-synuclein aggregates respectively, that lead to neuronal cell death.
  Genetic studies of corneal endothelial dystrophies and development of alternative treatment options
  Dr M Ali
Applications accepted all year round

Funding Type

PhD Type

The cornea is the protective front part of the eye that provides most of the eyes focusing power. The endothelium is a single-cell layer on the inside of the cornea that maintains fluid balance and is required for corneal transparency.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  MRC DiMeN Doctoral Training Partnership: Understanding proteotoxicity of alpha- and gamma-synuclein in neuronal C. elegans models of neurodegeneration
  Dr P van Oosten-Hawle, Prof S E Radford
Application Deadline: 6 January 2020

Funding Type

PhD Type

Synucleopathies, such as Parkinson’s Disease (PD), are neurodegenerative diseases characterised by the accumulation of alpha-synuclein (asyn) aggregates into Lewy Bodies in neurons, leading to toxicity and cell death.
  MRC DiMeN Doctoral Training Partnership: Understanding zinc-dependent regulation of TRPC5 channels and its role in diabetes
  Dr R.S. Bon, Dr S Muench, Dr P Sukumar
Application Deadline: 6 January 2020

Funding Type

PhD Type

TRPC5 ion channels are emerging drug targets, for example for CNS disorders, renal disease, cancer and cardiovascular disease (Cells 2018, 7, pii.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  MRC DiMeN Doctoral Training Partnership: Use of 3D skin models and patient-derived immune cells to elucidate the molecular mechanisms of skin detachment in severe drug-induced skin adverse reactions
  Dr D Carr, Prof D Naisbitt, Prof A Dickinson
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening skin adverse drug reactions which can be caused by a multitude of prescriptions drugs.
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