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We have 29 Biochemistry (differentiation) PhD Projects, Programmes & Scholarships

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Biochemistry (differentiation) PhD Projects, Programmes & Scholarships

We have 29 Biochemistry (differentiation) PhD Projects, Programmes & Scholarships

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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more
 Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences
Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more
 Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering human tissue in vitro: development, characterisation, and application

Durham University Department of Biosciences
Tissues in the human body have a defined structure in that their growth and differentiation have developed in specific ways to create a cellular architecture… Read more
 Supervisor: Prof S Przyborski
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences
T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more
 Supervisor: Dr T Ly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more
 Supervisor: Dr G Findlay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role and regulation of membraneless granules for the development of T. brucei

University of York York Biomedical Research Institute
Adaptation to a change of environment is an essential process for survival, in particular for parasitic organisms exposed to a wide range of hosts. Read more
 Supervisors: Dr M Cayla, Dr P B Walrad
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Graphene oxide as growth factor carriers for meniscus tissue engineering

The University of Manchester Faculty of Biology, Medicine and Health
Damage to the meniscus of the knee leads to increased risk of osteoarthritis. Tissue engineering of a healthy meniscal fibrocartilage offers the opportunity to restore function. Read more
 Supervisors: Dr H Lu, Dr S Richardson, Prof P Xiao
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more
 Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Understanding centrosome assembly in healthy and cancerous tissue with imaging

University of Leicester Molecular and Cell Biology
This is an opportunity for a scientist to join the lab of Dr Robert Mahen in the Department of Molecular & Cell Biology at the University of Leicester. Read more
 Supervisor: Dr R Mahen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences
Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more
 Supervisor: Dr M Isanejad
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of the extracellular matrix in cardiomyocyte developmental (SMITH_U24DTP1)

University of East Anglia Norwich Medical School
Primary Supervisor: Dr James Smith . Secondary Supervisor: Dr Iain Macaulay (EI) . Cardiomyocytes are the muscle cells of the heart, responsible for the production of contraction forces. Read more
 Supervisor: Dr J Smith
 9 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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PhD candidate - Origin of Obesity and Metabolic Disorders in Childhood (f/m/x)

Helmholtz Zentrum Munich Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)
We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Read more
 Supervisor: Prof S Körner
 22 March 2025  PhD Research Project  Funded PhD Project (Students Worldwide)
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Chromatin regulation of oncogenic transcription and replication stress: mechanism and functional implications in acute myeloid leukemia

University of Liverpool Institute of Systems, Molecular and Integrative Biology
This project focuses on the molecular mechanisms promoting acute myeloid leukaemia (AML), a disease of great unmet need. AML is an aggressive blood and bone marrow cancer characterized by abnormal proliferation and differentiation of myeloid cells. Read more
 Supervisors: Dr M Papamichos Chronakis, Prof D MacEwan, Dr A Kanhere
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the Therapeutic Potential of Cannabidiol (CBD) in Cardiac Fibrosis

University of Reading School of Pharmacy
Cardiac fibrosis is a condition that is characterized by the abnormal accumulation of fibrous tissue within the heart muscle and poses a significant threat to cardiovascular health. Read more
 Supervisors: Dr G Cottrell, Prof D Widera
 31 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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