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We have 18 Biochemistry (epithelial) PhD Projects, Programmes & Scholarships

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Biochemistry (epithelial) PhD Projects, Programmes & Scholarships

We have 18 Biochemistry (epithelial) PhD Projects, Programmes & Scholarships

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How to build and maintain a 3-dimensional polarised epithelial sheet

University of Nottingham School of Life Sciences
We are interested in how cells maintain normal cell shape within an epithelium. Correct epithelial cell shape is essential to maintain tissue integrity and when deregulated can cause diseases such as malignant cancers, diabetes, inflammation, and aging. Read more
 Supervisor: Dr M Georgiou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Live cell imaging of epithelial cancer cell proliferation for therapy

University of Leeds Faculty of Biological Sciences
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Prof A Divan, Dr S Ponnambalam, Dr M A Harrison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanism of vimentin induced epithelial mesenchymal transition (EMT) and stemness in cancer cells

Queen Mary University of London Institute of Dentistry
Background. Most cancers are epithelial in origin and arise from a single progenitor cell, similar to an embryo, to become a clone of cells. Read more
 Supervisors: Prof A Waseem, Dr H Tummala, Dr F Flores-Borja
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Possible role of mutant vimentin in cancer progression and metastasis

Queen Mary University of London Institute of Dentistry
Background. This project will investigate the role of the cytoskeletal protein vimentin in cancer progression and metastasis using cell and molecular biology approaches. Read more
 Supervisors: Prof A Waseem, Dr F Flores-Borja, Dr H Tummala
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School
Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more
 Supervisors: Dr S. J. Jones, Dr M Islam
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Disrupted SUMO signalling in epithelial cancers, implications for genome stability and response to therapy.

University of Leeds Faculty of Biological Sciences
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisor: Dr A Garvin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy
Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-funded MSc R- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine
The mechanisms driving heterogeneity and stemness during cellular transformation. Read more
 Supervisor: Dr A Essafi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Self-funded PhD- The mechanisms driving heterogeneity and stemness during cellular transformation.

University of Bristol School of Cellular and Molecular Medicine
The mechanisms driving heterogeneity and stemness during cellular transformation. Read more
 Supervisor: Dr A Essafi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling the role of genotoxic E. coli in colorectal cancer (SCHULLERS_U24BIGC)

University of East Anglia Norwich Medical School
Primary supervisor - Dr Stephanie Schüller. Secondary supervisor - Prof Nathalie Juge. Colorectal cancer (CRC) is the third most common and second most fatal cancer globally. Read more
 Supervisor: Dr S Schüller
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

University of Reading Department of Food and Nutritional Sciences
This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more
 Supervisors: Prof R A Frazier, Dr R Green
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Role of mechanical signals in a 3D human model of alveolar differentiation

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships
Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more
 Supervisors: Dr S Loukogeorgakis, Dr F Michielin, Prof P De Coppi
 15 May 2024  PhD Research Project  Funded PhD Project (UK Students Only)
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Inorganic chaperones fused to fungal derived chemotherapeutic agents for the treatment of neuroblastoma

University of Salford School of Science, Engineering and Environment
Information on this PhD research area can be found further down this page under the details about the Widening Participation Scholarship given immediately below. Read more
 Supervisors: Dr R Arrigo, Dr S Namvar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy
Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more
 Supervisor: Prof L Martin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

University of Leeds Faculty of Medicine and Health
The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more
 Supervisors: Dr G Mavria, Dr S Bell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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