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Biochemistry (human) PhD Projects, Programs & Scholarships

We have 246 Biochemistry (human) PhD Projects, Programs & Scholarships

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  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  (MRC DTP) Developing a zebrafish model for a novel human neurodevelopmental disorder
  Prof G D Pavitt, Dr P Kasher, Dr S Banka
Application Deadline: 15 November 2019

Funding Type

PhD Type

Background. We have recently discovered a novel human disorder caused by mutations in the EIF5A1 gene resulting in developmental problems, small head size and craniofacial defects in children [1].
  Molecular regulation of surface remodelling in the human pathogen Schistosoma mansoni
  Prof A Walker
Applications accepted all year round

Funding Type

PhD Type

In this PhD project you will perform cutting edge research that aims to identify molecular signalling events that underpin the survival of schistosomes in their human host.
  Molecular mechanisms regulating the developmental plasticity of pancreatic cancer cells #NDORMS-2020/6
  Dr S Pauklin
Application Deadline: 10 January 2020

Funding Type

PhD Type

Pancreatic cancers are among the most lethal malignancies in human due to highly metastatic characteristics and the poor responsiveness to currently used cancer therapeutics.
  The relationship between dietary iron and zinc, and the gut microbiota: Can dietary iron and zinc regime be exploited to improve health?
  Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"The gut microbiota (100 trillion cells) outnumber human cells by 10 to 1. Its composition of around 500 to 1000 species is specific for each individual and is dynamic, changing with age, health and diet.
  Regulation of T cell immunity in human barrier tissues - PhD position in Munich
  Prof C Zielinski
Application Deadline: 15 December 2019

Funding Type

PhD Type

The Technical University of Munich (TUM) is one of the most renowned Universities in Europe. The research group is located in a prestigious newly built research building, TranslaTUM, which is dedicated to interdisciplinary translational research.
  (MRC DTP) RAC1 mutations in human neurodevelopmental syndrome: from mechanism to treatment
  Dr T Millard, Dr S Banka, Dr S Woolner, Prof V Allan
Application Deadline: 15 November 2019

Funding Type

PhD Type

RAC1 regulates a variety of essential cellular functions1,2,3. We recently showed that it is critical for normal human development by discovering a novel neurodevelopmental syndrome caused by mutations in the RAC1 gene4.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  Mass spectrometry analysis of human tissue to characterise cleavage events resulting in amyloid deposition associated with aortic aneurysm and dissection
  Dr J Madine, Prof C E Eyers
Applications accepted all year round

Funding Type

PhD Type

The most common form of localised amyloid occurs in the aorta (aortic medial amyloid; AMA) and is estimated to occur in 97% of Caucasian people over 50.
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
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