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Biochemistry (innate) PhD Projects, Programs & Scholarships

We have 43 Biochemistry (innate) PhD Projects, Programs & Scholarships

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  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 10 January 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 10 January 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  MRC DiMeN Doctoral Training Partnership: How does the human innate immune system kill the Streptococcus pneumoniae bacterium during infection?
  Dr A Fenton, Dr L Prince
Application Deadline: 6 January 2020

Funding Type

PhD Type

Background. The bacterium Streptococcus pneumoniae is a highly successful human pathogen and a leading cause of pneumonia, a disease responsible for millions of deaths every year.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  EASTBIO Understanding the rules of mitochondrial nucleic acid escape in innate immune activation
  Dr A Dhir, Dr S Tait
Application Deadline: 5 January 2020

Funding Type

PhD Type

Mitochondria are the ‘power-stations’ of our cell, providing energy for cellular function. Mitochondria have evolved from ancient bacteria that invaded our cells a billion of years ago and have ‘integrated’ into our biological system in an endosymbiotic relationship.
  Proteolytic network regulating the human innate immune response
  Dr D Boucher, Prof I Hitchcock
Application Deadline: 30 June 2020

Funding Type

PhD Type

The innate immune system is our first line of defence against a wide range of bacteria and viruses. Upon infection, immune cells, such as macrophages and neutrophils, will assemble signalling platforms termed inflammasome, to restrict and clear the insult.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam
  Dr M Soller
Applications accepted all year round

Funding Type

PhD Type

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response.
  Precision Medicine DTP – Investigating disease causing mutations in PNPase- an approach to understand mitochondrial nucleic acid driven auto-inflammation
  Research Group: Centre of Genomic and Experimental Medicine
  Dr A Dhir, Dr S Tait, Dr T Chandra
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. Mitochondrial diseases are a heterogeneous class of disorders often characterized by failure of mitochondrial function and loss of energy associated with respiratory chain complex deficiency.
  Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways.
  Prof N J Gay
Applications accepted all year round

Funding Type

PhD Type

This group participates in the Wellcome Trust 4 year PhD programme in Developmental biology., MRC and BBSRC Doctoral Training Programmes.
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