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We have 19 Biochemistry (metal) PhD Projects, Programmes & Scholarships

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Biochemistry (metal) PhD Projects, Programmes & Scholarships

We have 19 Biochemistry (metal) PhD Projects, Programmes & Scholarships

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Chemical modification of proteins via metal-mediated processes

Chemically modified proteins can be used to understand, treat, and diagnose disease. However, relatively few chemical reactions can be used to modify proteins, severely limiting the diversity and applications of new technologies. Read more

Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Electro-bioluminescence for integrated milk biosensors

 Electro-bioluminescence for integrated milk biosensors. The PhD project will develop an integrated electro-bioluminescent sensing technology for the simultaneous detection of lactose, micro and macro nutrients (metal ions and vitamins) in breast milk samples. Read more
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Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

New Methods for modelling cofactor-dependent enzyme structure and function

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

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