Biochemistry (mice) PhD Projects, Programmes & Scholarships

We have 19 Biochemistry (mice) PhD Projects, Programmes & Scholarships

Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences

Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more

Supervisor: Dr D Wilkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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The effect of early-life stress on cardiac function in later life

University of Dundee School of Medicine

Stressful experiences in early childhood can increase the risk of cardiovascular disease (CVD) in later life. How early-life stress (ELS) influences susceptibility to CVD onset remains largely unknown. Read more

Supervisors: Dr N Fraser, Dr C Murdoch, Prof T Hales

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Protecting cells from mechanical stress: A novel role of cell-surface receptor LRP1 in extracellular matrix- nuclei communication.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Cellular adaptation to mechanical strain (mechano-adaptation) is increasingly understood to be conferred by Lamin intermediate filament proteins located within the nuclear lamina. Read more

Supervisor: Dr K Yamamoto

Year round applications PhD Research Project Self-Funded PhD Students Only

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Funded PhD - Determining the genetic and circadian basis of bipolar disorder

University of Bristol School of Physiology, Pharmacology & Neuroscience

This project will be part of the University of Bristol - University of Kent Cotutelle Programme. It will be jointly supervised by Prof James Hodge (http://www.bristol.ac.uk/phys-pharm-neuro/people-new/hodge/) and Dr Alice French at the University of Bristol, and by Prof Gurprit Lall at University of Kent. Read more

Supervisors: Prof J Hodge, Dr AF French

12 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Osteoarthritis (OA) causes pain and disability and is the most prevalent age-related joint disorder worldwide but there are no disease-modifying drugs available. Read more

Supervisors: Dr K Yamamoto, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the cellular functions of Trappc9 in brain development and microcephaly

University of Liverpool Institute of Systems, Molecular and Integrative Biology

This PhD project will investigate the cellular functions of the Trafficking protein particle complex subunit 9 (Trappc9) and its roles in brain development. Read more

Supervisors: Dr A Plagge, Dr T Zech

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD candidate to study immune and oncogenic signaling in cellular and animal models (f/m/x)

Helmholtz Zentrum Munich Signaling and Translation (SAT)

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Read more

Supervisor: Prof D Krappmann

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Advancing translational cell therapy for Hirschsprung disease

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Clinical disorders characterised by neuronal loss or dysfunction in the gastrointestinal tract remain some of the most challenging to manage, with considerable morbidity and mortality and very limited treatments. Read more

Supervisors: Dr C McCann, Prof P De Coppi

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more

Supervisor: Dr M Isanejad

Year round applications PhD Research Project Self-Funded PhD Students Only

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The effect of low protein diet on the development of the neuromuscular system

University of Liverpool Institute of Life Course and Medical Sciences

Age-related sarcopenia is characterised by reduction in the number of myofibres and motor neurons and an additional weakening of the remaining fibres, causing reduction in muscle mass and function. Read more

Supervisor: Dr A Vasilaki

Year round applications PhD Research Project Self-Funded PhD Students Only

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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Supervisors: Dr S. J. Jones, Dr M Islam

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education

Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 19 Biochemistry (mice) PhD Projects, Programmes & Scholarships

Biochemistry (mice) PhD Projects, Programmes & Scholarships

We have 19 Biochemistry (mice) PhD Projects, Programmes & Scholarships

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