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We have 91 Biochemistry (model) PhD Projects, Programmes & Scholarships

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Biochemistry (model) PhD Projects, Programmes & Scholarships

We have 91 Biochemistry (model) PhD Projects, Programmes & Scholarships

Role of mechanical signals in a 3D human model of alveolar differentiation

Alveolar epithelial type I (AT1) and type II (AT2) cells are essential for normal lung function following birth. Abnormal differentiation of AT1 and AT2 cells during development results in pulmonary pathology with associated neonatal mortality and long-term morbidity. Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more

Investigating Neuropeptide Signalling From Synthesis to Survival

Neuropeptides, comprising of short amino acid chains, are potent bioactive molecules with extensive neuromodulatory functions and are predominantly expressed within the central nervous system. Read more

Biological rhythms and the dopamine system in cognitive dysfunction

  Research Group: Pharmacology and Experimental Therapeutics
Psychiatric disorders such as schizophrenia are associated with metabolic syndrome, obesity and diabetes. Schizophrenia affects 1.1% of the population and although not the most common psychiatric condition it is arguably the most severe and debilitating. Read more

Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more

Systems level analysis of platelet signalling

We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more

Systemic infections accelerate tau spreading by promoting glial activation

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

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