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Biochemistry (pharmacology) PhD Projects, Programs & Scholarships

We have 20 Biochemistry (pharmacology) PhD Projects, Programs & Scholarships

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We have 20 Biochemistry (pharmacology) PhD Projects, Programs & Scholarships

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CDK inhibitors as immunotherapeutic agents for cancer treatment

If you seek to advance your career in drug discovery for cancer immunotherapy, the University of South Australia—Australia’s University of Enterprise—is offering the opportunity to apply for a novel PhD project in collaboration with. Read more

Molecular Modelling and Pharmacology of G protein-coupled Receptors

Many physiological processes are controlled through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess spatially distinct allosteric sites that can be targeted by small molecule ligands to modulate the receptor biological state. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

Improved lipid analysis to inform future therapeutic strategies

The University of Nottingham has a long-standing reputation for world-class research. The School of Pharmacy is ranked 5th in the world (2021 QS World Rankings) for pharmacy and pharmacology and was recently awarded an Athena Swan Silver award. Read more

Investigation of aortic remodelling in obesity and role of mitochondrial dysfunction

Obesity is a global healthcare and economic burden with currently more than 650 million adults classified as obese (WHO, 2017). Obesity is a common precursor to type 2 diabetes (T2DM), and both are risk factors for developing cardiovascular disease. Read more

Polmorphisms in cytosolic drug metabolising enzymes: a combined proteomics and modelling approach to clinical impact

Cytosolic drug metabolising enzymes such as aldehyde oxidase play a pivotal role in metabolism of drugs. However, research into cytosolic enzymes has been relatively neglected in comparison with membrane bound enzymes such as cytochrome P450 (CYP) and uridine 5’-glucuronosyltransferases (UGTs). Read more

Therapeutic resolution of coronavirus (COVID-19) diseases by natural products

  Research Group: Pharmacology and Experimental Therapeutics
Coronavirus now labelled as Covid-19 has become a global pandemic affecting around 200 countries. Currently neither any cure nor any vaccine for Covid-19 has been established. Read more

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