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Biochemistry (screening) PhD Projects, Programs & Scholarships

We have 55 Biochemistry (screening) PhD Projects, Programs & Scholarships

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  Mechanism of interaction between phosphodiesterase type 5 inhibitors and selective oestrogen receptor modulators in human fibroblasts
  Prof S Cellek, Prof D Ralph
Application Deadline: 9 February 2020

Funding Type

PhD Type

This project is supported by colleagues in MTRC. Fibrosis is the overproduction of extracellular matrix proteins which can impedes the function of organs.
  Chemical biology tools for drug development
  Dr J Konvalinka, Dr P Sacha
Application Deadline: 23 February 2020

Funding Type

PhD Type

Laboratory of Jan Konvalinka looks for a PhD candidates to work on development of several novel chemical biology tools for drug design, target discovery and validation, compound screening and target protein visualization.
  Development of non-mammalian, pre-clinical screening tools for the predictive analysis of cardiotoxicity (WHEELERGU20NC3Rs)
  Dr G N Wheeler
Application Deadline: 14 February 2020

Funding Type

PhD Type

Potential new drugs developed to treat cancer, diabetes or any other disease can cause additional unwanted side effects including cardiotoxicity.
  Screening of chemical libraries using iPS models for investigating the role of prion protein in Alzheimer’s disease
  Prof B Chen
Applications accepted all year round

Funding Type

PhD Type

Background. AD has been identified as a protein misfolding disease (proteopathy). The disease is caused by accumulation of two major amyloids.
  (BBSRC DTP CASE) Intelligent Engineering of Bacterial Genomes
  Prof R Breitling, Prof E Takano
Application Deadline: 31 January 2020

Funding Type

PhD Type

The goal of this project is to establish methodology for the intelligent engineering of biological hosts for the production of high-value drugs and chemicals.
  Cloning and expression of topoisomerase genes from Trypanosoma brucei (SteverdingD-2U19SF)
  Dr D Steverding
Application Deadline: 31 May 2020

Funding Type

PhD Type

Topoisomerases (TOPs) are essential enzymes that catalysis topological changes in DNA. TOPs are pivotal to cell survival and therefore inhibitors have been developed to target these enzymes both for antimicrobial and anti-cancer chemotherapy.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  High-throughput mechanobiology
  Dr C Toseland
Applications accepted all year round

Funding Type

PhD Type

Cancer research has traditionally focused upon extra- or intra-cellular biochemical signals, and their relation to cancer development and metastasis.
  Ecology and technology of microbial fuel cells
  Prof T Bell, Prof K Hellgardt
Application Deadline: 12 February 2020

Funding Type

PhD Type

Bacteria can be used to generate electricity. Electrons are produced by bacteria as they decompose organic matter (the "fuel") under anaerobic conditions, and the electricity produced can be stored in a battery or used to power instruments.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
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