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Biochemistry (signal) PhD Projects, Programs & Scholarships

We have 34 Biochemistry (signal) PhD Projects, Programs & Scholarships

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  Cardiotoxicity of cancer drugs targeting the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade
  Prof A Clerk
Applications accepted all year round

Funding Type

PhD Type

"Heart failure is a leading cause of morbidity and mortality worldwide. The contractile cells of the heart, cardiomyocytes, possess many protective mechanisms, allowing them to withstand pathophysiological stresses.
  Characterisation of cell death pathways upon activation of the endoplasmic reticulum stress sensor IRE1alpha
  Dr M Schroeder
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD project to investigate cell death pathways activated by endoplasmic reticulum (ER) stress is available in the group of Dr.
  Control of Parathyroid Hormone Secretion
  Dr D Ward, Dr J Bruce
Applications accepted all year round

Funding Type

PhD Type

The regulation of parathyroid hormone (PTH) secretion is of fundamental importance for calcium homeostasis and in mineral conditions affecting bone and the kidneys.
  Fluorescence Lifetime Micro-endoscopic Camera System for Clinical Optical Imaging
  Dr R.K Henderson, Dr N Finlayson
Application Deadline: 27 June 2020

Funding Type

PhD Type

The EPSRC IRC Proteus (Proteus) - Multiplexed ’Touch and Tell’ Optical Molecular Sensing and Imaging - Lifetime and Beyond” is an Interdisciplinary Research Collaboration between the Universities of Edinburgh, Bath, Heriot Watt, Durham and Dundee.
  TRPM2 channel mechanism of neuroinflammation and neurodegeneration in Alzheimer’s disease
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr I Wood
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the most common cause of dementia and also a major cause of morbidity and mortality. Currently, there is no effective therapeutics to treat or slow the disease progress.
  The regulation of platelet function - towards new strategies to prevent thrombosis
  Prof J M Gibbins
Applications accepted all year round

Funding Type

PhD Type

Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding.
  Investigating the impact of hypoxia on T lymphocytes
  Dr S Ross
Application Deadline: 28 May 2020

Funding Type

PhD Type

PhD Studentship Opportunity – October 2020. The Babraham Institute is a world-leader in fundamental biological research investigating the systems that underpin development and healthy ageing.
  Developing and applying genetically encoded proteins as pre-resonant coherent Raman scattering tags for next-generation live-cell imaging
  Dr D Jones, Prof W Langbein, Prof P Borri, Dr P Watson
Application Deadline: 5 June 2020

Funding Type

PhD Type

EPSRC funded DTP PhD Studentship within the Interdisciplinary Doctoral Training Hub “Physics of Life”. The Hub is designed as a cross-disciplinary PhD research and training programme at the physics/life science interface.
  Building bionanohybrid circuits: understanding and applying single protein molecule function
  Prof J E Macdonald, Dr D Jones, Dr O Castell
Application Deadline: 5 June 2020

Funding Type

PhD Type

Merging ideas and principles from biology with the physical sciences has proved pivotal in improving our fundamental understanding of nature and the generation of new technologies that impact on our everyday lives.
  Unravelling the dynamics of lipid bilayers and membrane proteins and their reaction to toxins and viral infection on the single molecule level using label-free microscopy.
  Prof W W Langbein, Prof P Borri, Dr MY Young, Dr O Castell
Application Deadline: 5 June 2020

Funding Type

PhD Type

Approximately 30% of the proteins in a cell are membrane proteins, which represent more than 60% of all known drug targets and play a critical role in both infection and immunity.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  PhD Studentship: Detection of peroxynitrite using a reactive luminescent lanthanide probe
  Dr S Butler
Application Deadline: 22 August 2020

Funding Type

PhD Type

Application details. Reference number. CM/SJB-Un1/2020. Start date of studentship. 1st October 2020. Closing date of advert. 22th August 2020.
  A multiple modality approach for targeting treatment-resistant ovarian cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer (OvCa) deaths and its five-year survival rate is 43%.
  mRNA translation reprogramming and metabolic re-wiring in response to ribosome-targeted therapies
  Prof R. Pearson, Dr J Kang
Applications accepted all year round

Funding Type

PhD Type

Increased synthesis and activity of ribosomes are associated with oncogenesis downstream of the major oncogenes including MYC, RAS and PI3K.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
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