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Biochemistry (structural) PhD Projects, Programs & Scholarships

We have 73 Biochemistry (structural) PhD Projects, Programs & Scholarships

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We have 73 Biochemistry (structural) PhD Projects, Programs & Scholarships

NMR spectroscopy in structural biology

1.) NMR method development. NMR is a versatile technique that is used to study structure, dynamics and various functional aspects of proteins and their complexes with their interaction partners. Read more

Structural biology of the Ccr4-Not nuclease complex using electron paramagnetic resonance (EPR) spectroscopy and integrative modelling

The ultimate goal in molecular biology is to understand normal physiology and disease processes at atomic resolution. Methods such as x-ray crystallography and NMR spectroscopy have been phenomenally successful in the past decades and continue to be the workhorses of structural biology. Read more

Using cryoEM to understand pathogen antibiotic transport and resistance

Background. A number of dangerous pathogens are increasingly resistant to our front-line antibiotics, raising the prospect of a ‘post-antibiotic era’ where we can no longer treat infectious diseases. Read more

Ion channel clustering in neuronal membranes

The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions. Read more

Structural and functional analysis of DNA double strand break repair.

Eukaryotic cells have evolved complex molecular systems in order to detect and repair double-strand breaks (DSBs) of the DNA helix, which can arise from exposure to genotoxic agents or during normal nucleic acid metabolism. Read more

Structural analysis of the inter-membrane bacterial secretosome

Protein secretion is essential for life. Bacteria secrete proteins for a wide range of membrane and extracellular activities, including envelope biogenesis, pathogenicity and degradation of antibiotics. Read more

Neuroinflammation in Alzheimer’s disease: what is the role of amyloid-beta fibril structure?

This project will explore the role of amyloid-beta fibril structure in triggering neuroinflammation in Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia and affects millions worldwide. Read more

Unravelling the structure and conformational dynamics of membrane proteins using H/D-exchange mass spectrometry and cryo-EM

A dynamic studentship which includes experience working in both academic and pharmaceutical industry environments. the project is performed in partnership between laboratories at both King’s College London and UCB Pharma (Slough, 20 miles West of Central London). Read more

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