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Biochemistry (transcription) PhD Projects, Programs & Scholarships

We have 49 Biochemistry (transcription) PhD Projects, Programs & Scholarships

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  Effect of Mediator on transcriptional bursting
  Dr F Robert
Applications accepted all year round

Funding Type

PhD Type

Mediator is a universal transcriptional coactivator (Jeronimo and Robert, 2017; Soutourina, 2018). It is recruited to enhancers by sequence-specific transcription factors and allows communication between the enhancers and their target promoters.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Epigenetic regulation of meiotic genes by the transcription factor Hac1i
  Dr M Schroeder
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD studentship to investigate how the transcription factor Hac1i achieves epigenetic regulation of early meiotic genes is available in the group of Dr.
  PhD Studentship in Biosciences Institute – Understanding the role of transcription in organisation of bacterial chromosome
  Prof N Zenkin
Application Deadline: 5 February 2020

Funding Type

PhD Type

Number of awards. 1. Start date and duration. 28 September 2020. An early start date is possible. The funding covers a three year PhD.
  (BBSRC DTP) Development of anti-cancer agents and biomarkers that target intrinsically disordered regions of transcription factors and protein kinases
  Prof J Waltho, Dr A Almond
Application Deadline: 31 January 2020

Funding Type

PhD Type

The controlled manipulation of transcription factors, protein kinases and protein phosphatases is central to improving our understanding of cellular processes and, importantly, in the development of next-generation therapeutics for a variety of cancers.
  Effects of transcription on genome stability
  Prof N J Savery
Applications accepted all year round

Funding Type

PhD Type

Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  Investigating the role of tauopathy-induced activating transcription factor 3: a transcriptional hub to modulate neurodegeneration.
  Research Group: Neurosciences
  Dr K Deinhardt, Prof V M O'Connor
Application Deadline: 28 February 2020

Funding Type

PhD Type

Fully funded PhD position available to study the role of ATF3 in tau-mediated neurodegeneration. We have previously identified an upregulation of the transcription factor ATF3 in mouse models of neurodegeneration.
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  New ways of terminating transcription in bacterial pathogens
  Dr C Brown
Applications accepted all year round

Funding Type

PhD Type

An excellent PhD candidate (’A’ grades) interested in researching the fundamental process of gene expression in bacteria is being recruited to join a multidisciplinary team led at University of Otago, Dunedin, New Zealand.
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