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We have 30 Biochemistry (death) PhD Projects, Programmes & Scholarships

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Biochemistry (death) PhD Projects, Programmes & Scholarships

We have 30 Biochemistry (death) PhD Projects, Programmes & Scholarships

Investigation of the extracellular matrix as a regulator of Parkinson’s progression

  Research Group: Chemistry and Biosciences
Parkinson’s is the 2nd most common neurodegenerative disease, affecting around 1 in 20 people aged over 65. In the UK, the number of affected people is set to rise by 50% over the next 50 years due to ageing populations. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Laser-based fabrication of medical diagnostic devices in paper

The focus of our group’s research is the development of user-friendly sensors or devices for affordable and rapid clinical diagnostic testing at the point-of-care (POC) of a patient, i.e., at their hospital bedside or in a care/nursing home, or in ambulance or at home. Read more

Structural investigation of oncogenic splicing factors

More than 90% of human genes can and do express multiple proteins. This is achieved by a process called alternative RNA splicing, which is an essential step in gene expression in mammals. Read more

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Untying the knot: Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways

Open PhD position on Genome Stability and Biochemistry. Joint PhD scholarship - St Andrews and Bonn-Biology. Untying the knot. Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways. Read more

New strategies to cryopreserve cell-based therapies

In the past decade, cell-based therapies have emerged to transform the treatment of disease, particularly cancer. Whilst potent, these therapies are challenging to deliver in practise as must be stored frozen (cryopreserved). Read more

Investigating the Roles for deSUMOylation Enzyme SENP3 in Autophagy Impaired by α-synuclein

Aggregation of α-synuclein protein in neuronal cells has been strongly implicated in the pathogenesis of neurodegenerative disorders (Synucleinopathies) including Parkinson's disease and dementia with Lewy bodies. Read more

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