Biochemistry (human) PhD Projects, Programmes & Scholarships

We have 161 Biochemistry (human) PhD Projects, Programmes & Scholarships

Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Greenwich School of Pharmacy (Medway Campus)

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Deciphering the landscape of nucleoporin and lamin function in nucleocytoplasmic communication, nuclear scaffolding and transcriptional control in disease prevention

University of Kent Medway School of Pharmacy

The nucleus has an instrumental role in cellular responses by coordinating shuttling of components in and out of the nucleus and gene expression with genome architecture and stability. Read more

Supervisors: Dr F Papagiannouli, Dr G Lall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Uncovering the mechanisms of cryoprotectant toxicity and improving cryopreservation protocols

University of Birmingham Institute of Inflammation and Ageing

Cryopreservation is the process of placing cells, organs or even whole organisms at low temperatures so that they remain in a state of suspended animation and function is preserved. Read more

Supervisor: Prof JP Magalhaes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Translational Medicine: Understanding the mechanism(s) of resistance to EPA to personalise therapy and improve outcome

University of Leeds Faculty of Medicine and Health

Advanced colorectal cancer (CRC) is the UK’s second most lethal cancer, with limited treatment options for unresectable metastatic tumours. Read more

Supervisors: Dr MA Volpato, Prof M Hull

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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Systems level analysis of platelet signalling

University of Reading Department of Biomedical Sciences

We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more

Supervisors: Dr M J Fry, Prof J M Gibbins

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure-function relationships governing polyphenol bioactivity with respect to plasma membranes

University of Reading Department of Food and Nutritional Sciences

This project aims to investigate polyphenol binding to lipid membrane surfaces with a view to understanding how polyphenol structure and aggregation within the gastrointestinal tract (GIT) affects the bioavailability of these nutraceuticals. Read more

Supervisors: Prof R A Frazier, Dr R Green

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding control of genome folding by cohesin

University of Leicester Molecular and Cell Biology

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Supervisors: Prof D Panne, Dr T Schalch

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

University of East Anglia School of Biological Sciences

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Supervisor: Dr MS Sullivan

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(MRC DTP CASE) An Integrative Structural Biology Platform for Drug Discovery

The University of Manchester Faculty of Biology, Medicine and Health

Solute carriers (SLCs) are the second largest class of membrane-embedded proteins with over 400 members organised into 66 families. Read more

Supervisors: Dr A Politis, Dr CP Pliotas

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Systemic infections accelerate tau spreading by promoting glial activation

University of Southampton School of Biological Sciences

Alzheimer’s disease (AD) is a neurodegenerative disease, with a complex biology. In this PhD project, we aim to explore the cellular and molecular mechanisms underlying tau pathology. Read more

Supervisor: Prof J Teeling

17 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Treatment and biomarker development for inherited manganese transporter defects using cell models of SLC30A10 deficiency

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Manganese is essential to human health and development. However, excess manganese is neurotoxic causing manganism, a neurodegenerative disorder characterised by dystonia-parkinsonism. Read more

Supervisors: Dr K Tuschl, Dr P Mills, Dr WH Heywood

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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We have 161 Biochemistry (human) PhD Projects, Programmes & Scholarships

Biochemistry (human) PhD Projects, Programmes & Scholarships

We have 161 Biochemistry (human) PhD Projects, Programmes & Scholarships

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