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Biochemistry (3d) PhD Projects, Programs & Scholarships

We have 44 Biochemistry (3d) PhD Projects, Programs & Scholarships

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  3D Print and Additive Manufacturing of Wax and Plastic Injection Moulds.
  Dr E Sabet
Applications accepted all year round

Funding Type

PhD Type

This project offers a chance to work on a truly disruptive and innovative research project in the high-tech and high-value manufacturing, with very high potential impact in aerospace and energy sectors.
  Simulation Modelling of Distortion and Shrinkage in Stereolithography 3D Printing.
  Dr E Sabet
Applications accepted all year round

Funding Type

PhD Type

This project offers a chance to work on a truly disruptive and innovative research project in the high-tech and high-value manufacturing, with very high potential impact in aerospace and energy sectors.
  Manufacturing bio functional PEEK implants by 3D printing and surface functionalisation with bioactive peptides
  Dr L Veschini, Dr T Coward
Applications accepted all year round

Funding Type

PhD Type

Surgery to remove cancer in the head and neck regions can result in severe tissue defects that cannot regenerate spontaneously.
  3D Super-Resolution Correlative Light-Electron Microscopy of the Protein Complexes
  Prof Dirk-Peter Herten, Dr I Styles
Application Deadline: 28 February 2020

Funding Type

PhD Type

Inflammation plays an important role in the development and progression of cardiovascular diseases. The modulation of inflammation and immunity by CD4+ regulatory T-cells has therefore received increasing attention.
  MRC DTP 4 Year PhD Programme: Deciphering the role of oxidative stress in cardiovascular disease using physiological and 3D cell models.
  Dr C Murdoch, Dr C Henderson
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Creating 3D models of ARVC disease with light-induced tuneable severity in stem cell-derived cardiomyocytes
  Dr V GEORGE
Application Deadline: 27 February 2020

Funding Type

PhD Type

Applications are invited for a 3 year Non-Clinical BHF PhD studentship to work on the above project in Keele University, in the group of Dr.
  Using a novel 3D co-culture model to define metabolic flux maps of different cancer cell types in response to physical activity
  Dr M Morris, Dr A Islam, Prof M.P. Lewis
Applications accepted all year round

Funding Type

PhD Type

During exercise, and in the presence of sufficient oxygen, glucose is metabolised by muscle cells to produce pyruvate, a metabolic intermediate which is fed into the Kreb’s cycle in the mitochondria to produce large amounts of energy.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
  Dr C Francavilla, Prof S Hubbard
Applications accepted all year round

Funding Type

PhD Type

Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g.
  Tackling neurovascular dysfunction in dementia: a cell biology and biomaterials approach
  Prof N Hooper, Dr M Domingos, Dr T Wang
Applications accepted all year round

Funding Type

PhD Type

Neurovascular dysfunction is a central process in the pathogenesis of Alzheimer’s disease and other dementias. In the brain, vascular and neuronal structures are tightly integrated forming the multicellular neurovascular unit comprising endothelial cells, pericytes, astrocytes, microglia and neurons.
  Understanding and minimizing radiation damage in breast tissues
  Dr M Sherratt, Miss C Kirwan, Prof S Cartmell
Applications accepted all year round

Funding Type

PhD Type

Human beings are subjected to many forms of radiation both natural (principally ultraviolet radiation [UVR]) and artificial (diagnostic and therapeutic X-rays).
  Chronic Wounds and Infection - impact on diabetic patients
  Research Group: Centre for Skin Sciences
  Dr M J Thornton, Dr J N Fletcher
Applications accepted all year round

Funding Type

PhD Type

Non-healing chronic wounds present a significant clinical challenge. In Europe, the cost of wound management accounts for 2%–4% of the health care budget and the complications associated with impaired wound healing can have a significant, long-term effect on the morbidity, mortality, and quality of life for patients.
  Discovery of chemical and biological tools to probe hypoxic solid tumours
  Research Group: Institute of Cancer Therapeutics
  Dr K Pors, Dr J Elies Gomez
Applications accepted all year round

Funding Type

PhD Type

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells. One avenue towards the development of more selective cancer therapies is to exploit the unique physiological properties of solid tumours using prodrug approaches.
  Circadian control of secretory pathway function
  Prof D J Stephens
Applications accepted all year round

Funding Type

PhD Type

Cells are the fundamental unit of life. Our aim is to understand cell function in the context of membrane and cytoskeleton dynamics.
  Evolution and conservation of membrane-associated effector proteins in plant pathogens
  Dr CN Meisrimler
Application Deadline: 25 February 2020

Funding Type

PhD Type

We seek a PhD candidate to join a 3-year research program based at the University of Canterbury (UC) to investigate the 3D structure of effector proteins targeting the membrane associated NAC transcription factors.
  Anti-cancer activities of dietary phytochemicals (BaoY-PshezhetskiyDU19SF)
  Dr Y Bao, Prof D Pshezhetskiy
Application Deadline: 31 May 2020

Funding Type

PhD Type

Epidemiological studies show that dietary phytochemicals such as isothiocyanates (ITCs) derived from cruciferous vegetables can decrease the risk of many types of cancer.
  Bioinformatics studies of protein structures, functions and their interactions
  Dr L J McGuffin
Applications accepted all year round

Funding Type

PhD Type

The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease.
  ’Follow my leader’: in vitro studies of oral cancer cell motility
  Dr S Whawell, Dr H Colley
Applications accepted all year round

Funding Type

PhD Type

Oral cancer cell invasion is a crucial step in the progression of the disease and is mediated by interactions with the extra cellular matrix and factors released by the tumour cells as well as cells that occupy the tumour microenvironment (stroma).
  Development of Novel Crystallization Methods for Integral Membrane Proteins
  Dr G Patchornik
Applications accepted all year round

Funding Type

PhD Type

Our research is focused on one of the major barriers in Structural biology. growing high quality three dimensional (3D) crystals of integral membrane proteins for structural analysis.
  EPSRC Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

The CDT will train the next generation of leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.
  PhD position - Structural basis of melanogenesis enzymes
  Dr M Soler-Lopez
Applications accepted all year round

Funding Type

PhD Type

Ref. InnovaXN_17_ESRF. Categorisation. Places of work. - Grenoble, Rhône-Alpes, France. Contract type. Contract, start on 2020-09-07.
  FLuoroAromatic-Thiol Tags (FLA-SH Tags) as probes to understand protein folding, interactions and dynamics
  Dr C Coxon
Application Deadline: 28 February 2020

Funding Type

PhD Type

This project will explore the design, synthesis and optimisation of a new class of biocompatible cysteine-selective fluorinated probes to study protein conformation, dynamics, interactions, (mis-/un) folding and aggregation in real-time at the single molecule level using 19F NMR.
  FGFR signalling in breast cancer
  Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Growth factors are used during development to convey messages that tell cells to divide, survive, migrate and adopt a particular fate.
  In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
  Dr E Opara, Dr M Stolinski, Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Culinary herbs are foods rich in polyphenols and a significant body of work has reported on their (the foods) many properties as a consequence of these compounds.
  Towards a Tissue Engineered Model of a Joint on a Chip
  Prof M.P. Lewis, Dr A Capel
Applications accepted all year round

Funding Type

PhD Type

This research project aims to develop a multi-tissue platform that integrates many of the structural tissue components of a musculoskeletal joint; bone, tendon, muscle, cartilage and ligament.
  Vascularisation of tissue engineered skeletal muscle
  Prof M.P. Lewis, Dr A Capel
Applications accepted all year round

Funding Type

PhD Type

Tissue engineering strategies have created a large number of functional tissues constructed from cells and matrix components over the past two decades.
  EPSRC Centre for Doctoral Training in Engineered Tissues for Discovery, Industry and Medicine (LifETIME)

Funding Type

PhD Type

The CDT will train the next generation of leaders in developing in vitro tissues, sensing and diagnostics to develop humanised in vitro systems to drive better drug screening.
  Sustainable multifunctional polymer foams (Ref: SF20/APP/PERRY1)
  Prof J Perry
Applications accepted all year round

Funding Type

PhD Type

Chitin is the second most abundant biopolymer after cellulose it being found in the exoskeletons of insects and other invertebrates as well as providing structural rigidity to fungi.
  Modelling of Oral Neutrophil Epithelial interactions
  Dr E Hagi-Pavli
Applications accepted all year round

Funding Type

PhD Type

Background and Clinical Significance. Neutrophils are an important and vital cellular component of the innate immune system providing rapid protection against microbial invasion.
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