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Biochemistry (flow cytometry) PhD Projects, Programs & Scholarships

We have 37 Biochemistry (flow cytometry) PhD Projects, Programs & Scholarships

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Showing 1 to 30 of 37
  Analysing immune responses to metastatic ovarian tumours to identify therapeutic targets
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Investigating how ovarian tumours avoid immune responses in cancer patients
  Dr J H Caamano, Dr D Withers
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Ovarian cancer remains the most lethal gynaecological malignancy for women over 50 years old (1).
  Impact of Inflammatory Signals on the Regenerative, Anti-inflammatory and Immunomodulatory Potential of Human Mesenchymal Stem Cells and their Secretome
  Dr D Widera
Applications accepted all year round

Funding Type

PhD Type

Adult multipotent stem cells can be easily isolated from a variety of adult human tissues and organs including bone marrow and adipose tissue.
  Tissue antigen and immune cell turnover in health and disease
  Dr R Busch
Applications accepted all year round

Funding Type

PhD Type

A healthy immune system is in a state of restful homeostasis. Activation of the immune system, whether to fight infections or during immune-mediated diseases, involves substantial changes in the rates at which immune cells and proteins are produced and destroyed (turnover).
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  MHC class I antigen presentation in autoimmune diabetes mellitus
  Prof M Garstka
Application Deadline: 15 March 2020

Funding Type

PhD Type

A Ph.D. program starting in September 2020 is now open for the applications. The Ph.D. student will work with Prof. Malgorzata Garstka at the Medical School of Xi’an Jiaotong University, Xi’an, China.
  Funded Research MPhil (fees-only) on Epigenetics of Acute Myeloid Leukaemia
  Dr C Pina
Application Deadline: 28 February 2020

Funding Type

PhD Type

The Centre for Genome Engineering and Maintenance (CenGEM) and Division of Biosciences at Brunel University London is offering a funded MPhil research studentship (fees-only) for the investigation of the cross-talk between DNA and histone modifications in the evolution of Acute Myeloid Leukaemia.
  Post-transcriptional regulation of transferrin receptor expression in Trypanosoma brucei
  Dr C Tiengwe
Applications accepted all year round

Funding Type

PhD Type

The goal of this project is to understand how. Trypanosoma brucei. controls expression of iron regulatory proteins in response to changes in intracellular iron.
  Transcription control and immune evasion in African trypanosomes
  Research Group: Division of Cell & Molecular Biology
  Prof G Rudenko
Applications accepted all year round

Funding Type

PhD Type

Trypanosomes are unicellular eukaryotes which cause African Sleeping Sickness, which is endemic to subSaharan Africa. Trypanosomes can be easily grown as suspension cell lines in the laboratory, where they are straightforward to manipulate and genetically modify.
  Micro-environmental Interactions And Non-Coding RNAs In The Biology Of B Cell Leukemia
  Prof M Mráz
Application Deadline: 20 February 2020

Funding Type

PhD Type

We are looking for motivated PhD students for a project funded by the prestigious ERC (European Research Council) Grant (laboratory of Assoc.
  Testing the function of immune suppressive cytokines and cells in bone metastasis
  Assoc Prof B Parker
Applications accepted all year round

Funding Type

PhD Type

Bone metastasis is a common occurrence in breast and prostate cancer that leads to patient morbidity and, in many cases, mortality.
  The role of the breast microenvironment in suppressing early cancer invasion
  Assoc Prof B Parker, Dr D Zanker
Applications accepted all year round

Funding Type

PhD Type

Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer, whereby the tumour cells remain restrained by myoepithelial cells that surround breast ducts.
  Therapy-induced senescence and stemness in ovarian cancer
  Prof R. Pearson, Dr K Chan
Applications accepted all year round

Funding Type

PhD Type

Cellular senescence is a stress response characterized by a robust cell cycle arrest and is a brake for malignant transformation.
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round

Funding Type

PhD Type

Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
  Investigating the mechanisms contributing to placental dysfunction in pregnancies complicated by diabetes: role of the hexosamine biosynthetic pathway
  Prof M Westwood, Prof J Aplin, Dr J Myers
Applications accepted all year round

Funding Type

PhD Type

Maternal diabetes is a major risk factor for fetal overgrowth, which is associated with poor outcomes including stillbirth, neonatal morbidity and increased risk of diabetes in adulthood.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  MSc by Research Programme: How do T cells maintain quiescence at the intestinal epithelial barrier?
  Dr M Swamy
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Modulation of platelet-mediated innate immune responses in chronic lymphocytic leukaemia
  Dr M Arman
Application Deadline: 31 March 2020

Funding Type

PhD Type

Chronic lymphocytic leukaemia (CLL) is the most common form of leukaemia in the Western World. B-cell receptor-induced intracellular signals are critical for the survival of leukaemia cells and disruption of this pathway by the Bruton’s tyrosine kinase (Btk) inhibitor ibrutinib is a highly effective CLL therapy.
  Platelets and hypoxia: how do varying oxygen concentrations affect platelet function and signalling?
  Dr M Arman
Applications accepted all year round

Funding Type

PhD Type

Platelets have key functions in regulating haemostasis and maintaining vascular integrity, which can cause cardiovascular disease if unbalanced.
  An integrated approach to the study of cellular interactions with amyloid
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr E W Hewitt, Prof S E Radford
Applications accepted all year round

Funding Type

PhD Type

The formation of insoluble amyloid fibrils is associated with a spectrum of human disorders, the amyloidoses, which include Alzheimer’s, Parkinson’s, type 2 diabetes and dialysis related amyloidosis (DRA).
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  Expression systems for pluripotent stem cells and their differentiated derivatives
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

Human pluripotent stem cells provide an opportunity to study normal development, to model disease and to generate cells and products for therapeutic use.
  In vitro models of type 1 diabetes.
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

Type 1 diabetes is a condition in which the immune system destroys the cells that produce insulin, the hormone controlling the level of glucose in the blood stream.
  Making B-lymphocytes form pluripotent stem cells. pervisor
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

B lymphocytes are a critical arm of the adaptive immune system. The in vitro generation of B cells from human pluripotent stem cells provides an opportunity to study normal immune development, to model disease and to generate cells and products for potential therapeutic use.
  Modelling T-cell Development using pluripotent stem cells
  Prof E Stanley, Prof AG Elefanty
Applications accepted all year round

Funding Type

PhD Type

T lymphocytes are a critical arm of the adaptive immune system. The in vitro generation of T cells from human pluripotent stem cells provides an opportunity to study normal immune development, to model disease and to generate cells and products for therapeutic use.
  Defining protein degradation machinery in the endoplasmic reticulum underlying resistance mechanisms in cancer
  Assoc Prof J Christianson, Prof Udo Oppermann
Application Deadline: 3 March 2020

Funding Type

PhD Type

Cellular stress is a hallmark of cancers. The restorative homeostatic response mechanisms that often become constitutively engaged, serve to adapt populations to hyperproliferative and metabolically dysregulated states, stabilise malignancy, and elevate resistance to therapeutic agents.
  FoodBioSystems DTP - Diet and Chronic Disease: mechanistic studies on the impact of dietary protein on gut barrier function and the microbiota.
  Dr M Lewis, Dr D Robertson, Prof B A Griffin, Dr G Walton
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. The gut microbiota is increasingly being linked to various chronic diseases including cardiovascular and liver disease.
  Biological role of neuropeptides and their receptors
  Dr L Lander
Applications accepted all year round

Funding Type

PhD Type

"Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well.
  Platelet-cell interactions: Platelets beyond thrombosis and haemostasis
  Dr A Pollitt
Applications accepted all year round

Funding Type

PhD Type

"Platelets play a key role in the prevention of bleeding following blood vessel damage.
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