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Biochemistry (infection biology) PhD Projects, Programs & Scholarships

We have 87 Biochemistry (infection biology) PhD Projects, Programs & Scholarships

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  A proteomic map of host cell rewiring by pathogens
  Dr B Collins, Prof J Bengoechea, Dr G Schroeder
Application Deadline: 31 March 2020

Funding Type

PhD Type

We aim to develop advanced methods in mass spectrometry-based proteomics and apply them to the question of how host cellular defences are manipulated by bacterial pathogens.
  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 24 July 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  Nucleic Acid Sensing During Virus Infection – Innate Immunity
  Dr J Rehwinkel
Application Deadline: 24 July 2020

Funding Type

PhD Type

Virus infection is a constant threat to the cells of all living organisms. To counter this threat, cellular receptors detect virus presence and activate potent antiviral immune responses.
  (WIS) How food-borne Listeria monocytogenes overcomes the host defence mechanisms at the single cell level?
  Prof I Roberts, Dr P Paszek
Application Deadline: 6 March 2020

Funding Type

PhD Type

Pathogens have developed intricate ways to overcome the host’s immune system. In this proposal we will study the direct interaction of macrophages with the important food-borne bacterial pathogen Listeria monocytogenes that causes significant human morbidity and mortality.
  Understanding the role of DRAM in infection and autophagy-related disease
  Dr J King, Dr P Elks
Applications accepted all year round

Funding Type

PhD Type

Intracellular degradation by lysosomes is important in a wide range of diseases. The capture and degradation of cytoplasmic components by autophagy allows tumour cells to survive starvation and neurons to remove the protein aggregates associated with neurodegeneration.
  Single-cell proteomic analysis of host-factor cleavage during norovirus infection
  Dr E Emmott, Dr M Iturriza
Applications accepted all year round

Funding Type

PhD Type

Human norovirus is a major human pathogen, and the causative agent behind ‘winter vomiting disease’. Typically, infection is self-limited, causing diarrhoea and vomiting lasting from 24-72 hours.
  MRC DTP 4 Year PhD Programme: Structural and developmental mechanics in polarized membrane trafficking
  Dr D H Murray, Dr J Januschke
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Cell biology of a bacterial nano-weapon
  Dr S Coulthurst, Dr C Rickman
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Defining the signalling pathways regulating intraepithelial lymphocytes in the gut
  Dr M Swamy, Dr I Moraga Gonzalez
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  Molecular mechanisms of herpesviral infection
  Dr A Golovanov
Applications accepted all year round

Funding Type

PhD Type

Herpes viruses are known to cause a wide range of human diseases, ranging from simple cold sores to cancer, Kaposi Sarcoma. Kaposi Sarcoma, for example, is a type of cancer which affects immunocompromised patients and is endemic in Africa, where it is linked with the spread of HIV infection and AIDS.
  MSc by Research Programme: Development of tools suited for the in vivo identification and study of protein Complexes in Phytophthora capsici, required for infection.
  Dr E Huitema
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  EMBL Australia Partnership PhD Program

Funding Type

PhD Type

Undertake interdisciplinary, postgraduate research for a PhD degree at Australia's top life science laboratories. Successful students will receive generous scholarships and travel grants while undertaking their PhD at an EMBL Australia laboratory in Melbourne, Sydney, Canberra or Adelaide.
  FoodBioSystems DTP - Can many biomarkers make light work of liver fluke parasite diagnostics?
  Dr P McVeigh, Dr R Morphew
Application Deadline: 6 March 2020

Funding Type

PhD Type

Research Group. FOODBIOSYSTEMS BBSRC DTP. Liver fluke parasites are a pervasive economic threat on UK sheep and cattle farms.
  Virulence factors in dermatophytes
  Dr A Bolhuis
Applications accepted all year round

Funding Type

PhD Type

Dermatophytosis is caused by fungi infecting keratinised tissues and represents the most common and disseminated group of mycoses.
  Defining strategies to promote immunity to multi-drug resistant Staphylococcus aureus.
  Dr L Prince
Applications accepted all year round

Funding Type

PhD Type

Staphylococcus aureus is a highly successful pathogen that can circumvent many aspects of immunity. White blood cells, including neutrophils, are a critical defence against infection and yet S.
  The chemical glycobiology of carbohydrate metabolism
  Prof R Field, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Carbohydrates are widespread in nature and fulfil many important biological functions. However, the biology of carbohydrates is much less well explored than that of nucleic acids and proteins.
  Evolutionary insights for engineering improved globin oxygen carriers
  Dr M Berenbrink, Dr J Madine
Applications accepted all year round

Funding Type

PhD Type

Around 2 million red blood cell units at a cost of 120.00 GBP per unit are transfused annually in England alone (http://www.nhsbt.nhs.uk/what-we-do/blood-transfusion/).
  MRC DTP 4 Year PhD Programme: Functions & Applications of a Novel Stem Cell Signalling Pathway
  Dr GM Findlay, Dr M Stavridis
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Targeting E3 ubiquitin ligases with small molecules
  Prof A Ciulli, Dr S Virdee
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  Determining novel molecular regulators of necrosis controlling premature cell death
  Dr Y Fan
Applications accepted all year round

Funding Type

PhD Type

Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases.
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Targeting pathogen subversion of cellular ageing to combat antimicrobial-resistant typhoid fever
  Dr D Humphreys, Dr T Darton
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial-resistant typhoid fever is fuelled by chronic Salmonella carriage. The world faces epidemics of untreatable typhoid fever caused by antimicrobial-resistant strains of Salmonella Typhi (~27 million cases/year).
  PhD-position
  Prof L Dölken
Application Deadline: 1 March 2020

Funding Type

PhD Type

At the Institute for Virology and Immunology of the University of Wuerzburg, Germany we offer a. PhD-position. within the RTG2581 (Metabolism, topology and compartmentalization of membrane proximal lipid and signalling components in infection (https://www.uni-wuerzburg.de/grk2581) starting 01.04.2020.
  Adaptation to oxidative stress in hepatitis C virus persistence: the role of IRES-dependent translation.
  Dr S-W Chan, Prof R Ford
Applications accepted all year round

Funding Type

PhD Type

Hepatitis C virus (HCV) causes a clinically important disease affecting 3% of the world population (Chan 2014). About 75% of the infection will develop into chronic hepatitis, which can then progress into fibrosis, cirrhosis and hepatocellular carcinoma.
  Exploiting druggability host spots in protein phosphatase targets
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round

Funding Type

PhD Type

In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
  Metals and host-pathogen interactions: the role of metal handling systems in the human gastrointestinal pathogen Campylobacter jejuni
  Dr J Cavet, Dr D Linton
Applications accepted all year round

Funding Type

PhD Type

Campylobacter jejuni is a globally important food-borne pathogen causing an estimated 400-500 million cases of acute human gastroenteritis each year.
  MRC DTP 4 Year PhD Programme: Deciphering the role of oxidative stress in cardiovascular disease using physiological and 3D cell models.
  Dr C Murdoch, Dr C Henderson
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Investigating mRNA cap regulation in pluripotency and differentiation
  Prof V Cowling, Prof T A Owen-hughes
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
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