We have 92 Biochemistry (information studies) PhD Projects, Programmes & Scholarships

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Biochemistry (information studies) PhD Projects, Programmes & Scholarships

We have 92 Biochemistry (information studies) PhD Projects, Programmes & Scholarships

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

Discovering off-target side-effects and drug repurposing candidates using expression perturbation data

University of Bristol Bristol Medical School

The MRC Integrative Epidemiology Unit at the University of Bristol is the leading group for the development and application of causal analysis and evidence triangulation in health research to improve lives. Read more

Supervisor: Prof T Gaunt

20 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

PhD studentship - Defining the mechanisms underpinning HIF-1 and HIF-2 dependent transcriptional specificity in hypoxia.

Newcastle University Biosciences Institute

Award summary. 100% of home tuition fees paid and annual living expenses of £18,622. Overview. The cellular response to low oxygen levels (hypoxia), is crucial for cell survival and identity. Read more

Supervisor: Dr B Ortmann

14 June 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

The role of extracellular vesicles and intercellular signalling in inherited kidney cancer

Cardiff University Cardiff School of Medicine

This is a Self-Funded/Sponsored PhD opportunity. FUNDING REQUIRED. Full UK/EU or International Tuition Fees. UK Living Expenses. Bench Fees (£60,000 total). Read more

Supervisor: Dr E Dunlop

31 May 2024 PhD Research Project Self-Funded PhD Students Only

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

The University of Manchester Department of Chemistry

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

Supervisors: Dr S Lovelock, Dr C Markin

31 May 2024 PhD Research Project Funded PhD Project (Students Worldwide)

Last chance to apply

Sustainable bio-hydrogen production via engineered microbial metabolism (4-year fully funded PhD studentship with Dstl)

University of Edinburgh School of Biological Sciences

Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology

Background and the project. In 2022, carbon emissions from the chemical industry peaked at 935 M ton, making this industry the third largest sector by emissions and responsible for 2.5% of total greenhouse gas emissions worldwide. Read more

Supervisor: Prof S Wallace

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

FAIROmics - PhD fellowship in Food Microbiology - Omics-driven investigation of unique features of olive fermentation isolates beneficial for plant fermentation with probiotic properties.

INRAE Inrae - Paris-Saclay Food and Bioproduct Engineering Research Unit

About the Project. Plant-based dairy and meat alternatives have grown in popularity in recent years for various reasons, including sustainability and health benefits, as well as lifestyle trends and dietary restrictions. Read more

Supervisors: Dr KA Karatzas, Dr MWB Wells-Bennik, Dr MD Dasenaki, Prof VV Valdramidis

15 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Funding for the Executive Dean’s PhD Studentship: Lineage tracing of blood stem cell development in embryo-like gastruloids

Brunel University London Life Sciences

The team of Cristina Pina (https://www.brunel.ac.uk/people/cristina-pina), Alessandro Esposito (https://www.brunel.ac.uk/people/alessandro-esposito) and… Read more

Supervisor: Dr C Pina

10 June 2024 PhD Research Project Funded PhD Project (UK Students Only)

FAIROmics - PhD fellowship in plant-based food fermentation genomics.

INRAE Inrae - Paris-Saclay Food and Bioproduct Engineering Research Unit

About the Project. Plant-based dairy and meat alternatives have grown in popularity in recent years for various reasons, including sustainability and health benefits, as well as lifestyle trends and dietary restrictions. Read more

Supervisors: Dr MWB Wells-Bennik, Dr HB Bachmann, Dr EH Hester, Prof M Zwietering, Prof VV Valdramidis, Dr MD Dasenaki, Dr KA Karatzas

15 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Last chance to apply

Repurposing Treg cells for TIL therapy

The University of Manchester Faculty of Biology, Medicine and Health

Tumour-infiltrating lymphocytes (TIL) therapy is an experimental therapy which uses ex-vivo expanded TIL as a source of living drug to treat cancer. Read more

Supervisors: Dr A Hurlstone, Prof M Travis, Prof R Edmondson, Prof F Thistlethwaite

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

University of Dundee School of Life Sciences

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

30 June 2024 PhD Research Project Self-Funded PhD Students Only

Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Supervisors: Dr S Cogo, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

Fully-funded PhD Studentship in Controlling Transport of Colloidal Particles in Complex Fluids in Microfluidic Devices

Lancaster University School of Engineering

Supervisors. Primary supervisor. Dr Naval Singh, School of Engineering (Chemical Engineering). Secondary supervisor. Dr John Hardy, Department of Chemistry. Read more

Supervisors: Dr N Singh, Dr J Hardy

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

MSc by Research: Targeted protein degradation in plants – developing “Green PROTACs” for functional analysis of lethal genes

University of Dundee School of Life Sciences

Climate change is one of the biggest threats to global food production, leading to unpredictable weather patterns and geographical migration of pathogens. Read more

Supervisor: Dr P Hemsley

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Molecular mechanisms underlying aphid effector virulence activity

University of Dundee School of Life Sciences

Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more

Supervisor: Dr J Bos

Year round applications PhD Research Project Self-Funded PhD Students Only

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Supervisor: Dr M Soller

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences

Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more

Supervisors: Dr M Young, Dr J Parker

Year round applications PhD Research Project Self-Funded PhD Students Only

Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more

Supervisors: Dr D Ramji, Dr T Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

Functions of cyclin-dependent kinase 11 (CDK11) in regulation of gene expression and tumorigenesis

Masaryk University Faculty of Medicine

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. CDK11 is ubiquitously expressed in all tissues and the CDK11 null mouse is lethal at an early stage of development indicating an important role for Cdk11 in the adult as well as during development. Read more

Supervisor: Dr D Blažek

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis

Masaryk University Faculty of Medicine

Doctoral study program. Life Sciences. Research area. RNA/nucleic acids research in health, cancer biology. Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. Read more

Supervisor: Dr D Blažek

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

PhD Students (f/m/d) for super-resolution microscopy-based investigations of the glycocalyx

Max Planck Institute for the Science of Light PhD Opportunities

The Max Planck Institute for the Science of Light research covers a wide range of topics, including nonlinear optics, quantum optics, nanophotonics, photonic crystal fibres, optomechanics, quantum technologies, biophysics, and links between physics and medicine. Read more

Supervisor: Dr LM Möckl

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

University of Reading Department of Biomedical Sciences

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Supervisor: Dr S Boateng

Year round applications PhD Research Project Self-Funded PhD Students Only

Self-funded PhD- Re-engineering Golgi dynamics in plants – investigating the role of myosin receptors

University of Bristol School of Biological Sciences

The growing global population requires the development of novel strategies to sustainably increase food production. Organelle movement is dynamic and linked to changes in cell size, plant biomass and in response to factors which affect food production such as pathogens (Perico and Sparkes, New Phytol. Read more

Supervisor: Dr I Sparkes

Year round applications PhD Research Project Self-Funded PhD Students Only

Self-funded PhD- Exploring the Mechanisms of Bacterial Pathogen Entry and Colonization in Plants through Wounds

University of Bristol School of Biological Sciences

How bacterial pathogens enter and colonise plant via wounds?. Wounding of plants by hard wind, hail, heavy rain, sand storms, and frost is common in nature. Read more

Supervisors: Dr P Buscaill, Dr A Bailey

Year round applications PhD Research Project Self-Funded PhD Students Only

Self-funded PhD- Integrated multi-omics characterisation of human retroviral reservoirs

University of Bristol School of Cellular and Molecular Medicine

Human retroviruses are a group of pathogens infecting an estimated 50 million people worldwide. The most widespread human retrovirus is HIV-1, which remains a major cause of morbidity and mortality, particularly in developing countries. Read more

Supervisor: Dr IL Shytaj

Year round applications PhD Research Project Self-Funded PhD Students Only

Viral-surface interactions studied by vibrational sum-frequency spectroscopy

The University of Manchester Department of Materials

The recent COVID-19 pandemic, and in particular fomite transmission of the virus, led to a lot of interest in how viral particles attached to surfaces, their survival times on different materials and how they transferred to hosts. Read more

Supervisors: Dr A Thomas, Dr R Lindsay

Year round applications PhD Research Project Self-Funded PhD Students Only

Oncology: Evaluating Photodynamic Therapy in colorectal cancer using patient-derived organoids

University of Leeds Faculty of Medicine and Health

Colorectal cancer (CRC) is the 3rd most common cancer worldwide. Surgery is first line treatment and often in adjunct with chemotherapy. Read more

Supervisors: Dr I Knot, Prof D Jayne

Year round applications PhD Research Project Self-Funded PhD Students Only

Cancer Biology: The role of Wnt signaling in glioblastoma therapeutic resistance

University of Leeds Faculty of Medicine and Health

Glioblastoma is a deadly brain tumour treated with surgery, radiotherapy and chemotherapy with patient survival of 6-15 months. Read more

Supervisors: Dr G Mavria, Dr S Bell, Dr C Toomes

Year round applications PhD Research Project Self-Funded PhD Students Only

Genetics: Unravelling the Norrin/beta-catenin signaling pathway and its role in retinal angiogenesis and blindness

University of Leeds Faculty of Medicine and Health

Our previous work on the genetic analysis of individuals with the inherited retinal disease Familial Exudative Vitreoretinopathy (FEVR), has helped identify a new angiogenesis pathway, the Norrin/beta-catenin pathway. Read more

Supervisors: Dr C Toomes, Dr J Bond, Dr S Bell

Year round applications PhD Research Project Self-Funded PhD Students Only

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