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Biochemistry (medical microbiology) PhD Projects, Programs & Scholarships

We have 74 Biochemistry (medical microbiology) PhD Projects, Programs & Scholarships

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Showing 1 to 30 of 74
  Investigating a parasite-specific gene expression mechanism for the identification of novel anthelmintic drug targets
  Dr B Mueller, Dr J Pettitt, Dr B Connolly
Application Deadline: 13 March 2020

Funding Type

PhD Type

Nematode parasites remain a major cause of neglected human disease and make significant global impacts on the health of agriculturally important animals and plants.
  The mechanism of DNA organisation mediated by cohesion and condensin
  Dr B Hu, Prof A Donaldson
Application Deadline: 13 March 2020

Funding Type

PhD Type

The DNA of all organisms must be compacted in order to store a large amount of genetic information in one cell. Compaction must be regulated to allow access of DNA replication or transcription machinery, but to enable suitable condensation for effective chromosome segregation into two daughter cells at mitosis.
  What determines tumour susceptibility to replication-inhibiting chemotherapy?
  Prof A Donaldson, Dr S R Dundas
Application Deadline: 13 March 2020

Funding Type

PhD Type

Chromosome replication and maintenance are central for cell division, and derailment of these processes is a major cause of cancer.
  High-throughput discovery of novel antibiotics using synthetic microbiology
  Dr R Draheim
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is a frequent problem in the treatment of disease caused by several clinical bacterial pathogens. In the European Union, antibiotic-resistant infections kill nearly 25,000 patients and represent a total expenditure of £1.5 billion per year.
  Using synthetic biology to understand the evolution of antibiotic resistance
  Dr M Lagator, Dr C Knight
Applications accepted all year round

Funding Type

PhD Type

Imagine an architect, tasked with converting an old stadium into a building with a different function, without demolishing it.
  Protease-resistant antimicrobial peptides to target bacterial and fungal pathogens
  Dr J Bella, Dr L Tabernero
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance is quickly becoming a serious global health problem. The emergence of multidrug-resistant microbial strains combined with the drying up of the antibiotic pipeline in the pharmaceutical industry has significantly worsened the situation in recent years.
  Discovery of novel pharmaceuticals from marine and desert microorganisms
  Prof M Jaspars, Dr R Ebel
Applications accepted all year round

Funding Type

PhD Type

Microorganisms from extreme environments such as the deep seas, cold seas and hyper arid deserts have been shown to produce a range of complex natural products with high biological activity.
  Combining omega-3 docosahexaenoic acid and melatonin to manage spinal cord injury-induced central neuropathic pain.
  Dr W Huang, Prof H Galley
Application Deadline: 29 February 2020

Funding Type

PhD Type

About half of spinal injury patients develop neuropathic pain, which is driven by neuroinflammation, has no effective treatments, and impacts significantly on daily functioning.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens
  Dr J Blair
Applications accepted all year round

Funding Type

PhD Type

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation.
  The role of pore-forming bacterial proteins in pneumonia and meningitis
  Prof T J Mitchell, Dr M Tomlinson
Applications accepted all year round

Funding Type

PhD Type

The bacterium Streptococcus pneumoniae (the pneumococcus) is carried in the nasopharynx of most children and some adults without causing disease.
  Tackling antibiotic resistance: developing a vaccine against gonorrhoea
  Prof J P Derrick, Dr F Hayes
Applications accepted all year round

Funding Type

PhD Type

Gonorrhoea is caused by the Gram-negative bacterium Neisseria gonorrhoeae and is a serious public health problem in developing and developed countries.
  MRC DTP 4 Year PhD Programme: Bacterial stress sensing and antibiotic action
  Dr U Zachariae, Dr M Bergkessel
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP iCASE PhD Project: Characterisation of novel niraparib resistance mechanisms in ovarian cancer
  Dr G Smith, Dr M Ferguson
Application Deadline: 13 March 2020

Funding Type

PhD Type

We invite applications from outstanding biological or biomedical sciences graduates for a fully-funded 3.5-year MRC Doctoral Training Programme iCASE PhD studentship, in collaboration with GlaxoSmithKline (GSK), starting in September 2020, based in the Jacqui Wood Cancer Centre in the University of Dundee School of Medicine, Ninewells Hospital & Medical School.
  MSc by Research Programme: Development of tools suited for the in vivo identification and study of protein Complexes in Phytophthora capsici, required for infection.
  Dr E Huitema
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Characterisation of the genotype and phenotype of epithelial cells invaded by the periodontal pathogen Porphyromonas gingivalis.
  Dr S Whawell, Dr G Stafford
Applications accepted all year round

Funding Type

PhD Type

The presence of the Gram negative anaerobe Porphyromonas gingivalis is consistently associated with the more severe forms of periodontal disease and its ability to invade host epithelial cells is thought to be important in the pathogenesis of the disease.
  Developing an enzymatic toolbox to make complex modified peptides
  Prof M Jaspars, Dr W Houssen, Dr L Trembleau
Applications accepted all year round

Funding Type

PhD Type

The pharmaceutical industry has identified a major gap in its portfolio. On the one hand, they are excellent at discovering small molecules that act via a lock and key type mechanism.
  Functional characterization of Neisserial toxin-antitoxin systems
  Dr N Oldfield, Dr D Turner
Applications accepted all year round

Funding Type

PhD Type

Toxin-antitoxin (TA) systems are commonly found in both Gram-positive and Gram-negative bacteria and comprise a stable toxin able to stall bacterial replication and an antitoxin that neutralises the activity of the toxin.
  Type 1 Resistant Starch: A journey through the gut (EDWARDSQ20CASE)
  Dr C Edwards, Prof A Narbad
Application Deadline: 23 March 2020

Funding Type

PhD Type

Most adults in the UK are overweight or obese, and healthier processed foods are urgently needed. One solution is to replace ‘available starch’ in the diet with ‘resistant starch’ that is not readily digested to glucose in the upper-gut, and therefore enters the colon.
  Analysis and Treatment of Orthopaedic Pin Site Infections
  Dr J McEvoy
Applications accepted all year round

Funding Type

PhD Type

Pin site infections are a major complication of external fixation of fractures, and bacterial biofilms are known to form on the pin surface.1 This project, in collaboration with Dr Shobana Dissanayeke (RHUL) and St Peter’s Hospital, Chertsey, will investigate bacterial biofilms that have been obtained from percutaneous pins used in orthopaedic fixation frames.
  MRC DTP 4 Year PhD Programme: Cell biology of a bacterial nano-weapon
  Dr S Coulthurst, Dr C Rickman
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Deciphering the role of oxidative stress in cardiovascular disease using physiological and 3D cell models.
  Dr C Murdoch, Dr C Henderson
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Defining the signalling pathways regulating intraepithelial lymphocytes in the gut
  Dr M Swamy, Dr I Moraga Gonzalez
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Functions & Applications of a Novel Stem Cell Signalling Pathway
  Dr GM Findlay, Dr M Stavridis
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: How does the ubiquitin system ensure a healthy proteome in cells?
  Dr Y Kulathu, Dr A Rousseau
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Interdisciplinary investigation of the role of amino acids in immunometabolic responses to metformin in human macrophages
  Dr G Rena, Prof C Lang
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Interrogating the interdependence of the cell cycle and the segmentation clock
  Prof J K Dale, Dr P Murray
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Investigating mRNA cap regulation in pluripotency and differentiation
  Prof V Cowling, Prof T A Owen-hughes
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: O-GlcNAcylation and protein (mis)folding
  Dr D M F Van Aalten, Dr L McGurk
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
  MRC DTP 4 Year PhD Programme: Passive and active DNA demethylation pathways in stem cells and human diseases
  Dr K Rasmussen, Dr S Virdee
Application Deadline: 13 March 2020

Funding Type

PhD Type

This project is offered as part of the University of Dundee 4-year MRC DTP Programme “Quantitative and Interdisciplinary approaches to biomedical science”.
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