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We have 16 Biochemistry (medicinal) PhD Projects, Programmes & Scholarships

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Biochemistry (medicinal) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (medicinal) PhD Projects, Programmes & Scholarships

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

How to regulate plasticity in the brain

The Kwok Lab at the School of Biomedical Science invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Polysialyltransferases as a target in metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more

Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more

MSc by Research: Glueing proteins together with small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

Understanding interactions of proteins with polymer-coated nanoparticles

Introduction. Polymer-coated nanoparticles are promising drug delivery vehicles. Multiple functionalities can be embedded into the nanoparticle structure to enable uptake of the drug-like molecules, their targeted delivery and controlled release. Read more

Mining the Hippo signalling pathway for novel anti-cancer therapeutics

Candidates are invited to join the Kadri Lab, where our research focuses on developing innovative chemical approaches for discovering novel therapeutics to address unmet global health needs. Read more
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