We have 38 Biochemistry (metabolism) PhD Projects, Programmes & Scholarships

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Biochemistry (metabolism) PhD Projects, Programmes & Scholarships

We have 38 Biochemistry (metabolism) PhD Projects, Programmes & Scholarships

The development and application of metabolomics tools to study human metabolism in health and disease

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Metabolites play many important roles in humans including through metabolism to support our growth and health, through incorporation of lipids in cell membranes to influence transport of biochemicals in to and out of cells and to regulate biochemical processes. Read more

Supervisors: Prof WB Dunn, Dr H Muhamad Ali

31 July 2024 PhD Research Project Self-Funded PhD Students Only

Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Supervisor: Dr P Crichton

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Engineering more water-use efficient crops: functional genomics of CO2 fixation during Crassulacean acid metabolism

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The world is getting hotter and drier due to climate change, and the human population is growing rapidly. Furthermore, it has been predicted that we will need to increase crop yields by 50 - 70 % by 2050 in order to feed the predicted 9 - 10 billion people. Read more

Supervisors: Dr J Hartwell, Dr P Walley

Year round applications PhD Research Project Self-Funded PhD Students Only

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

University of East Anglia School of Biological Sciences

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Supervisor: Dr MS Sullivan

31 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

Last chance to apply

Sustainable bio-hydrogen production via engineered microbial metabolism (4-year fully funded PhD studentship with Dstl)

University of Edinburgh School of Biological Sciences

Research Group: Institute of Quantitative Biology, Biochemistry and Biotechnology

Background and the project. In 2022, carbon emissions from the chemical industry peaked at 935 M ton, making this industry the third largest sector by emissions and responsible for 2.5% of total greenhouse gas emissions worldwide. Read more

Supervisor: Prof S Wallace

22 April 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

PhD candidate - Origin of Obesity and Metabolic Disorders in Childhood (f/m/x)

Helmholtz Zentrum Munich Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health. Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Read more

Supervisor: Prof S Körner

22 March 2025 PhD Research Project Funded PhD Project (Students Worldwide)

Investigating Dietary Approaches to Improve Muscle Health

Royal Holloway, University of London School of Biological Sciences

The maintenance of good muscles health provides a key aspect of general health. Reduced muscle health is associated with both ageing and a range of diseases. Read more

Supervisors: Prof R S B Williams, Dr AB Malerba

Year round applications PhD Research Project Competition Funded PhD Project (UK Students Only)

Self-funded PhD- Integrated multi-omics characterisation of human retroviral reservoirs

University of Bristol School of Cellular and Molecular Medicine

Human retroviruses are a group of pathogens infecting an estimated 50 million people worldwide. The most widespread human retrovirus is HIV-1, which remains a major cause of morbidity and mortality, particularly in developing countries. Read more

Supervisor: Dr IL Shytaj

Year round applications PhD Research Project Self-Funded PhD Students Only

Targeting dormant cancer cells in myeloma

University of Sheffield School of Medicine and Population Health

Multiple myeloma is the second most common blood cancer and remains essentially incurable. Chemotherapy is effective at reducing tumour and extends survival, but it never fully eradicates disease, so patients face inevitable relapse. Read more

Supervisors: Dr A Green, Prof S El-Khamisy

31 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Last chance to apply

For the love of spice - plant secondary metabolites and recruitment of bacterial metabolic networks

Max Planck Institute for Chemical Ecology International Max Planck Research School

Background. Recruitment of bacteria to plant organs like leaves is important for plant development, health and survival. Understanding these processes is likely to be important for developing tools for more sustainable agriculture. Read more

Supervisors: Dr M Agler, Prof S.E.O. O'Connor

18 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions

University of Liverpool Institute of Life Course and Medical Sciences

Optimal tissue and organ is essential for long-term health and quality of life. One such important regulator within the body is related to circadian rhythms, which control ~24h cycles in many physiological processes such as sleep/wake cycles, physical activity/rest cycles, drug metabolism and hormones. Read more

Supervisor: Dr VPV Pekovic-Vaughan

Year round applications PhD Research Project Self-Funded PhD Students Only

Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

The University of Manchester Department of Chemistry

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

Supervisor: Dr C Megarity

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

The Importance of Muscle Stem Cells: Implications for Muscle Repair in Inflammation and Trauma

University of Nottingham School of Medicine

Skeletal muscle possesses a remarkable capacity for adaptation and repair, processes essential in the maintenance of skeletal muscle health. Read more

Supervisors: Dr S Joanisse, Prof P Greenhaff, Dr JM Mallinson, Dr C Deane

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford Faculty of Life Sciences

Research Group: Institute of Cancer Therapeutics

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more

Supervisors: Prof R Falconer, Prof P Loadman

Year round applications PhD Research Project Self-Funded PhD Students Only

Ion channel signalling in cancer cells

University of York York Biomedical Research Institute

Our cells constantly sense and transport ions present in their environment. From embryonic development to epilepsy to heart disease to cancer, our cells’ ability to respond to changes in the ionic microenvironment is essential for healthy ageing. Read more

Supervisor: Dr W Brackenbury

Year round applications PhD Research Project Self-Funded PhD Students Only

Investigating the role of dietary fructose in the development of early-onset colorectal cancer

University of Bristol Bristol Medical School

Project Background. This project will investigate the role of fructose in the development of early-onset colorectal cancer (EOCRC) in adults <50 years. Read more

Supervisors: Dr E Vincent, Dr A Chambers, Dr R Richmond, Dr NM Murphy

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Investigating the role of lactate in tuberculosis disease

University of Birmingham Institute of Inflammation and Ageing

About the project. We are seeking talented, hard-working and motivated students with a passion for research in Immunology, Metabolism and Infectious diseases to join the team led by Dr Alba Llibre (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/llibre-alba.aspx). Read more

Supervisors: Dr A Llibre Serradell, Prof C Mauro

Year round applications PhD Research Project Self-Funded PhD Students Only

(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Understanding the roles of triacylglycerol in modulating mycobacterial growth and biophysical properties

University of Leicester Department of Respiratory Sciences

Mycobacteria contain more lipid than any other bacteria. In addition to a characteristically lipid-rich cell envelope, mycobacteria can accumulate triacylglycerol (TAG) as cytoplasmic lipid bodies (LBs). Read more

Supervisors: Dr N Garton , Dr G Mukamolova

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Fully funded PhD studentship: Transforming respiratory care at the bedside using machine learning assisted on-chip vibrational spectroscopy

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team. Prof. Senthil Murugan Ganapathy. Project description. Acute respiratory distress syndrome (ARDS), a widespread respiratory condition affecting all ages, causes respiratory failure due to inflamed, fluid-filled lungs hindering gas exchange. Read more

Supervisor: Prof S Ganapathy

Year round applications PhD Research Project Competition Funded PhD Project (European/UK Students Only)

The Role of Nutrition and Exercise in Physical and Cognitive Function (such as sarcopenia and frailty), utilizing clinical, metabolomic, proteomic, and gut microbiota data

University of Liverpool Institute of Life Course and Medical Sciences

Physical frailty is a result of hallmarks of aging, where gut microbiome (GM) dysbiosis and dietary pattern play a significant role. Read more

Supervisor: Dr M Isanejad

Year round applications PhD Research Project Self-Funded PhD Students Only

PhD studentship - Defining the mechanisms underpinning HIF-1 and HIF-2 dependent transcriptional specificity in hypoxia.

Newcastle University Biosciences Institute

Award summary. 100% of home tuition fees paid and annual living expenses of £18,622. Overview. The cellular response to low oxygen levels (hypoxia), is crucial for cell survival and identity. Read more

Supervisor: Dr B Ortmann

14 June 2024 PhD Research Project Funded PhD Project (European/UK Students Only)

Geomicrobiological controls on radionuclide speciation and fate during the geodisposal of radioactive waste

The University of Manchester Department of Earth and Environmental Sciences

Context. The UK has been generating electricity from nuclear power for over sixty years. Consequently, the safe disposal of the UK’s existing ~750,000 m3 of radioactive waste is a clear priority. Read more

Supervisors: Prof J Lloyd, Prof S Shaw, Dr A Uknnl

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre

The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more

Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly

10 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Translating protection of cell-surface receptor LRP1 into potential disease-modifying therapies for osteoarthritis.

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Osteoarthritis (OA) causes pain and disability and is the most prevalent age-related joint disorder worldwide but there are no disease-modifying drugs available. Read more

Supervisors: Dr K Yamamoto, Prof G Bou-Gharios

Year round applications PhD Research Project Self-Funded PhD Students Only

Pathophysiology of intensive care acquired muscle weakness - the role of mitochondrial dysfunction

Charles University Third Faculty of Medicine

Department of Anaesthesia and Intensive Care Medicine, Third Faculty of Medicine, Charles University. Our research group is currently seeking a highly motivated Ph.D. Read more

Supervisors: Dr A Krajčová, Prof F Duška

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

Microbial Hydroponics - Novel Hydroponics Using Microbial Fuel Cells

University of Southampton Faculty of Engineering and Physical Sciences

Supervisory Team: Yannis Ieropoulos, Yue Zhang, Paul Kemp . Project Description. Read more

Supervisor: Prof Y Ieropoulos

31 July 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

Unravelling the Intricacies of Stress Hormone Regulation

University of Reading Department of Biomedical Sciences

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more

Supervisor: Dr A B Bicknell

Year round applications PhD Research Project Self-Funded PhD Students Only

Pectin supplementation to reduce gut and systemic inflammation and improve liver, muscle and gastrointestinal outcomes

University of Nottingham School of Medicine

A quarter of the world's population has metabolic dysfunction-associated steatotic liver disease, (which used to be known as non-alcoholic fatty liver disease). Read more

Supervisors: Prof G Aithal, Dr J Grove, Dr KR Rollins, Prof AMV Valdes

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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