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Biochemistry (metabolism) PhD Projects, Programs & Scholarships

We have 49 Biochemistry (metabolism) PhD Projects, Programs & Scholarships

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  Targeting the Role of Myeloid Steroid Metabolism in Chronic Inflammation
  Dr R Hardy, Dr P Foster
Applications accepted all year round

Funding Type

PhD Type

Background. Myeloid derived cell populations such as macrophages play a critical role in the early innate immune response, whilst dendritic cells are essential in bridging the progression to an adaptive immune response.
  Targeting steroid metabolism to block colorectal cancer proliferation
  Dr P Foster, Dr L Cox
Applications accepted all year round

Funding Type

PhD Type

Our group is a world leader in targeting specific aspects of steroid metabolism to block cancer growth. Our research has been instrumental in the successful pre-clinical and clinical development of various novel anti-cancer compounds.
  Development of a novel 3D gut-microbiota model for the assessment of absorption and metabolism of health supplements and therapeutic drugs
  Dr P Ragazzon
Application Deadline: 10 December 2019

Funding Type

PhD Type

The gut epithelium is a complex setting of intestinal cells and epithelial cells filled with transporters, enzymes and channels; these cells are then populated by bacteria (microbiota) that help with the metabolism of nutrients and transport into the blood stream.
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
  Determinants of Fat Metabolism During Exercise
  Dr C Shaw, Prof JW Helge
Application Deadline: 30 August 2019

Funding Type

PhD Type

This is a unique and exciting opportunity to complete a PhD across two leading laboratories researching exercise and muscle metabolism.
  Defining diets to treat inborn errors of metabolism
  Dr T Johnson, Dr M Piper
Applications accepted all year round

Funding Type

PhD Type

Fully funded PhD scholarships are available for both Australian and international students through the School of Biological Sciences and Monash University.
  The role of glucocorticoid desulfation in chronic inflammatory disease pathophysiology
  Dr P Foster, Dr R Hardy
Applications accepted all year round

Funding Type

PhD Type

Chronic inflammatory diseases (CIDs) are a common group of highly disabling immune conditions leading to persistent inflammation and tissue-specific manifestations, such as ulcerative colitis and arthritis.
  Vitamin D and immunometabolism
  Prof M Hewison, Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Vitamin D has potent anti-inflammatory and antibacterial immune effects.
  Quantitative Allele-Specific Proteomics in Drug Metabolism and Disposition
  Dr J Barber, Dr B Achour, Prof A Rostami
Applications accepted all year round

Funding Type

PhD Type

The effective dose of a drug is subject to considerable inter-individual variation because the enzymes that metabolise drugs and the proteins that transport them in and out of cells exist, in many cases, in different polymorphic forms and are expressed in varying concentration.
  How does amino acid metabolism affect tumour growth?
  Dr L. Cheng
Applications accepted all year round

Funding Type

PhD Type

The effect of diet on tumour growth is hotly debated but poorly characterized. Due to the heterogeneous nature of the tumours, dietary studies in patients with varied genetic background often led to inconclusive outcome.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Development of novel artificial intelligence algorithms for network wide metabolic flux analysis with stable isotope tracers
  Dr C Ludwig, Dr S He
Applications accepted all year round

Funding Type

PhD Type

The efficient function of the metabolic network in eukaryotic cells relies on its separation into a number of closely-linked but metabolically distinct compartments.
  Metabolic control of T cell function
  Dr S Dimeloe
Applications accepted all year round

Funding Type

PhD Type

Current research interests in Sarah Dimeloe’s lab focus on the metabolism and interlinked immune function of T lymphocytes in health and disease.
  Hijacking of host cellular functions and metabolism in MRSA pathogenesis
  Dr M Letek, Dr V Behrends, Dr Y Calle
Applications accepted all year round

Funding Type

PhD Type

Applications are invited from potential PhD candidates to work at the Department of Life Sciences, University of Roehampton, supervised by Dr Michal Letek, Dr Volker Behrends, and Dr Yolanda Calle-Patino.
  Cutting off the fuel supply to starve cancer: Identifying metabolic vulnerabilities in cancer
  Dr K Brown, Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

A universal characteristic of all cancer cells is the reprogramming of cell metabolism to provide the energy and building blocks necessary to support proliferation and survival.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  The Gut Microbiota and Colorectal Surgery
  Dr M Lewis, Prof S C Andrews
Applications accepted all year round

Funding Type

PhD Type

"Background. Antibiotic use prior to and following colorectal surgery is conventional practice, and is aimed at reducing the incidence of postoperative infection which is a major risk of such surgery.
  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  Adipose tissue remodelling in obesity and type 2 diabetes
  Dr K K Y Cheng
Applications accepted all year round

Funding Type

PhD Type

Background. Due to the changes in lifestyle and environment, the incidence of obesity has rapidly increased over the last two decades.
  Design, synthesis and evaluation of protease-activated anti-cancer prodrugs
  Research Group: Institute of Cancer Therapeutics
  Dr R Falconer, Prof P Loadman
Applications accepted all year round

Funding Type

PhD Type

Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis.
  Is there a switch between prostamides and prostaglandins in women with dysmenorrhoea and heavy menstrual bleeding?
  Prof K Marshall, Dr D Fischer, Prof A Nicolaou
Applications accepted all year round

Funding Type

PhD Type

Dysmenorrhoea, painful menstrual cramps, and heavy menstrual bleeding are common debilitating symptoms in women with or without an underlying pelvic pathology.
  Metabolomic studies of E. coli adaptation from anaerobic to aerobic growth
  Prof M P Williamson
Applications accepted all year round

Funding Type

PhD Type

Escherichia coli is a commensal organism that lives in the human gut. Occasionally it gives rise to food poisoning incidents, but mainly it is important for digestion and uptake of nutrients.
  Investigating metabolic changes in neurodegeneration
  Dr F Mackenzie, Dr M Stolinski
Applications accepted all year round

Funding Type

PhD Type

This 3-year PhD will study the increasingly recognised association between metabolic disease and neurodegeneration using in vitro cell culture methods.
  PhD program in Molecular Inflammation, Molecular Medicine and Advanced Medical Biomarker Research

Funding Type

PhD Type

Projects starting March 1, 2020. Application deadline. September 15, 2019.
  EMBL Australia Partnership PhD Program

Funding Type

PhD Type

Undertake interdisciplinary, postgraduate research for a PhD degree at Australia's top life science laboratories. Successful students will receive generous scholarships and travel grants while undertaking their PhD at an EMBL Australia laboratory in Melbourne, Sydney, Canberra or Adelaide.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round

Funding Type

PhD Type

The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  Elucidating the protein interaction network of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  Metabolic reprogramming and chemotherapy resistance in triple-negative breast cancer
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

Treatment options for the triple-negative breast cancer (TNBC) subtype of breast cancer are limited to conventional chemotherapy agents.
  Using T cells to eradicate cancer
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in immuno-oncology and the development of novel immunotherapeutic approaches for the treatment of cancer.
  Plant responses to stress, metabolites for health and fuel from cell walls.
  Prof A Devoto
Applications accepted all year round

Funding Type

PhD Type

Projects are available in the following areas. Stress responses in crops and sustainable biomass production and processing. The project aims at elucidating several aspects of the control of plant defences and to identify environmentally friendly forms of plant protectants, leading to enhanced crop yields.
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