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Biochemistry (php) PhD Projects, Programs & Scholarships

We have 18 Biochemistry (php) PhD Projects, Programs & Scholarships

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  Molecular insights into a novel mammalian oxygen-sensing pathway (Ph.D in Biochemistry/Chemical Biology)
  Dr M White, Prof R Payne, Prof J Mackay
Applications accepted all year round

Funding Type

PhD Type

Outstanding candidates with a background in biochemistry, molecular biology, organic chemistry or similar are invited to apply for a fully funded Ph.D scholarship…
  How protective signals from the gut modify neuronal activity and behaviour, using C. elegans as a model system.
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr P van Oosten-Hawle, Prof N Cohen
Applications accepted all year round

Funding Type

PhD Type

Amyloid protein misfolding leading to loss of neuronal function are fundamental pathogenic mechanisms of numerous age-associated neurodegenerative diseases, including Alzheimer’s (AD).
  Beyond Making Thiazolines and Oxazolines: Expanding the Enzymatic Repertoire to incorporate other 5- and 6-membered heterocyclic rings in peptides
  Dr W Houssen, Dr S Dall'Angelo, Dr I Fotheringham
Application Deadline: 1 May 2020

Funding Type

PhD Type

Cyclic peptides have a great therapeutic potential with several examples reach the clinic e.g. gramicidin S (antibiotic), ziconotide (pain relief), somatostatin (anticancer) and cyclosporine (immunosuppressant) and many others are in the late stages of clinical trials e.g.
  PhD Student - Functional Analysis of UHRF1 (f/m/d)
  Dr T Bartke
Applications accepted all year round

Funding Type

PhD Type

As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus, allergies and lung diseases.
  Investigate a novel, unexplored link between WNT signalling and regulators of cell migration in cancer progression using CRISPR-Cas9 and advanced live cell imaging.
  Dr M Krause
Applications accepted all year round

Funding Type

PhD Type

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. WNT signalling is a key pathway controlling morphogenesis in embryos and it has been shown that perturbations of this pathway promote cancer progression.
  Investigation of a probiotic strain of Lactobacillus plantarum 2025 and the development of novel antibacterials
  Prof A Karlyshev
Applications accepted all year round

Funding Type

PhD Type

Background. The rise of multidrug resistant forms of microbial pathogens imposes a serious problem to public health worldwide. The rapid spread of antimicrobial resistance is associated with misuse of conventional antibiotics.
  Precision Medicine DTP - Comprehensive study of miRNAs biogenesis in human cancer
  Dr G Michlewski, Dr C Kutter
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. MicroRNAs (miRNAs) are short non-coding RNAs ~22 nt in length that function as important regulators of gene expression1.
  Precision Medicine DTP - Defining and predicting the molecular basis for male infertility
  Research Group: MRC Human Genetics Unit
  Dr J Marsh, Dr J Welburn
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Male infertility is on the rise. While the genetics and molecular mechanisms underlying the phenomenon remain poorly understood, mutations in >75 human protein-coding genes have already been confidently linked to male infertility (Oud et al, 2019).
  Precision Medicine DTP – Investigating the metabolic alterations that initiate pre-neoplastic development in zebrafish and in humans
  Research Group: Centre for Inflammation Research
  Dr Y Feng, Dr K Burgess, Dr R Burchmore, Dr G Ho
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. “Warburg metabolism” is characterised by an increased uptake of glucose and its conversion to lactate by glycolysis under normoxia.
  Precision Medicine DTP - Proteomic analysis of FAK function in human pancreatic cancer
  Research Group: Centre for Inflammation Research
  Dr A Serrels, Dr A Byron, Dr A von Kriegsheim
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. In the United Kingdom, the 5-year survival rate for patients with pancreatic ductal adenocarcinoma (PDAC) is just 3% (Cancer Research UK statistics), and as a result pancreatic cancer is the 4th most common cause of cancer death in the UK and US.
  Precision Medicine DTP - Taming the Hippo in Cancer through Proteogenomics
  Research Group: Centre for Inflammation Research
  Dr C G Hansen, Prof J Lehtio
Application Deadline: 6 April 2020

Funding Type

PhD Type

Background. Pleural Mesothelioma is an asbestos-related cancer, and is one of the deadliest cancer types. Current methods of treatment and early diagnostics are ineffective.
  Control and inhibition of virus replication
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A.K Tuplin
Applications accepted all year round

Funding Type

PhD Type


The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specificaly Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets.
  Defining a novel assembly pathway in ssRNA viruses using X-ray footprinting.
  Prof P G Stockley
Applications accepted all year round

Funding Type

PhD Type

Project co-supervised by Prof. Peter Stockley at Leeds and Prof. Reidun Twarock at University of York, as part of the White Rose network "Structural and Mechanistic Biology at the RNA/Ligand Interface".
  Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens
  Research Group: Astbury Centre for Structural Molecular Biology
  Dr A O'Neill
Applications accepted all year round

Funding Type

PhD Type

Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine.
  Chemical and Biological Recycling of Plastics - Fully funded 48-months PhD studentships

Funding Type

PhD Type

Lack of sustainable plastic waste management strategies has led to the global plastic crisis being one of the major environmental and public health challenges of our time.
  Fundamental studies underpinning catalysis - Fully funded 48-months PhD studentships

Funding Type

PhD Type

These will range from gas-phase laser spectroscopic studies of small molecules interacting with single metal atoms, the deposition and study of sputtered metal nanoparticles, the study of molecules interacting with MOFs, reactions inside carbon nanotubes, and the study of “real” catalysts.
  Protein nanocompartments for advanced enzymatic catalysis (PhD in Chemical and Synthetic Biology)
  Dr Y H Lau
Applications accepted all year round

Funding Type

PhD Type

The University of Sydney is looking for outstanding candidates who are looking to apply for a PhD position in chemical and synthetic biology, in the group of Dr Yu Heng Lau (http://sydney.edu.au/science/people/yuheng.lau.php).
  Structural insights into ligand binding and channel gating in ATP-gated P2X7 receptor
  Research Group: School of Biomedical Sciences
  Dr L H Jiang, Dr S Muench
Applications accepted all year round

Funding Type

PhD Type

P2X7 receptor, belonging to the ATP-gated ion channel P2X receptor family, exhibits distinct functional and pharmacological properties that are crucial for its role in innate immunity and inflammatory diseases and cancers (Jiang et al., 2013; Caseley et al., 2014; Roger et al., 2014; Wei et al., 2018).
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