Biochemistry (recombinant) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (recombinant) PhD Projects, Programmes & Scholarships

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Fully-funded PhD in Biology EPSRC iCASE with FUJIFILM Diosynth Biotechnologies (FDBK): Development of modular chromatography strategies for the straight through purification of biotherapeutic recombinant proteins from E.coli

University of York Department of Biology

Lead supervisor: Dr Michael Plevin (Department of Biology). Co-supervisors: Dr John Oyekan (Department of Computer Science) and Christopher Fox (Fujifilm Diosynth Biotechnologies). Read more

Supervisor: Dr M Plevin

22 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Obtaining insights into how a signalling hub protein Ras activates multiple effectors

University of Leicester Molecular and Cell Biology

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Supervisors: Dr K Tanaka , Dr R Mahen

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

University of Leicester Molecular and Cell Biology

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

Supervisors: Dr JF Fox, Dr JH Hodgkinson

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Development of an ambient mass spectrometry platform for rapid mass spectrometry characterisation of proteins

University of Edinburgh School of Chemistry

A PhD studentship is available in the group of Dr. Read more

Supervisor: Dr D Clarke

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Modulation of host immune response by secreted proteins from parasitic worms

University of York York Biomedical Research Institute

Background. To establish chronic infection, parasitic worms manipulate their mammalian hosts’ immune system. This immune modulation is often mediated by excreted or secreted parasite glycoproteins (ES proteins). Read more

Supervisors: Dr CR Crosnier, Dr J Hewitson, Dr A Kay

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Supervisors: Dr H O'Hare, Dr N Garton

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Alpha-synuclein amyloid in Parkinson's disease: using Nanoinjection as a tool to study alpha-synuclein amyloid toxicity inside neurons

University of Leeds Faculty of Biological Sciences

Intraneuronal inclusions known as Lewy bodies are a hallmark of Parkinson’s disease. Amyloid fibrils formed by the misfolding of alpha-synuclein are the principal component of Lewy Bodies. Read more

Supervisors: Dr E W Hewitt, Prof S E Radford, Dr P Actis

Year round applications PhD Research Project Self-Funded PhD Students Only

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Manipulation of neuroimmune responses and behaviour by infectious agents

University of Leeds Faculty of Biological Sciences

This project is available exclusively to self-funded students who wish to commence study for a PhD in the academic year 2023/24. The project focuses on how infectious agents modify the individuals that they infect and how neuroimmune responses to infection moderate behaviour changes in warm-blooded animals and humans. Read more

Supervisors: Dr G Mcconkey, Dr S Clapcote

Year round applications PhD Research Project Self-Funded PhD Students Only

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Membrane protein-metabolite interactions important in mitochondrial energy metabolism for burning fat as heat (CRICHTON_U24DTP)

University of East Anglia Norwich Medical School

Primary supervisor - Dr Paul Crichton . Secondary supervisor - Prof. Tom Clarke (UEA) . Mitochondria in our cells harness energy through the breakdown of nutrients to produce ATP through oxidative phosphorylation. Read more

Supervisor: Dr P Crichton

9 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences

Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more

Supervisor: Dr D Wilkinson

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure and function of enzyme complexes involved in post-transcriptional gene regulation

University of Nottingham School of Pharmacy

Many proteins in human cells function as part of high molecular weight multi-subunit assemblies. The structure and function of such large molecular machines is often difficult to characterise due to their complexity, low abundance and structural dynamics. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma

University of Nottingham School of Pharmacy

Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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Discovery and profiling of small-molecule inhibitors of cellular nuclease enzymes

University of Nottingham School of Pharmacy

Nuclease enzymes are non-traditional drug targets that attract an increasing amount of interest as potential targets relevant for a variety of therapeutic areas including infection, cancer and bone disease. Read more

Supervisor: Dr G S Winkler

Year round applications PhD Research Project Self-Funded PhD Students Only

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4-year PhD Studentship: Combatting bacterial zoonoses through multi-disciplinary studies of virulence factors

University of Bristol Bristol Veterinary School

Vector-borne diseases, including bacterial zoonoses, pose a significant threat to human and animal health and to livestock industries, particularly in low and middle-income countries. Read more

Supervisor: Dr T Cogan

Year round applications PhD Research Project Self-Funded PhD Students Only

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Characterisation of PA protease from Micrococcus luteus as a novel approach to the management of eczema

The University of Manchester Faculty of Biology, Medicine and Health

The chronic inflammatory skin disease, eczema, now affects approximately 15% of the paediatric population of the Western world and is growing in prevalence. Read more

Supervisors: Prof CN O'neill, Prof A McBain

Year round applications PhD Research Project Self-Funded PhD Students Only

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Engineering Ice-Binding Proteins

The University of Manchester Department of Chemistry

Ice-binding proteins are produced by extremophiles to help them survive in the worlds coldest places. They have many potential applications, from the storage of cells/tissue to transport infrastructure. Read more

Supervisor: Prof m Gibson

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 16 Biochemistry (recombinant) PhD Projects, Programmes & Scholarships

Biochemistry (recombinant) PhD Projects, Programmes & Scholarships

We have 16 Biochemistry (recombinant) PhD Projects, Programmes & Scholarships

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