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FindA University Ltd Featured PhD Programmes
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Biochemistry (repair) PhD Projects, Programs & Scholarships

We have 19 Biochemistry (repair) PhD Projects, Programs & Scholarships

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  Actin regulation of nuclear mechanics during DNA repair
  Dr C Toseland
Applications accepted all year round

Funding Type

PhD Type

In eukaryotic cells, the nucleus houses the genomic material and transcription machinery that allows the cell to develop and perform its role.
  DNA replication, recombination and repair in Archaea
  Dr T Allers, Dr E Bolt
Applications accepted all year round

Funding Type

PhD Type

Additional Supervisor. Anita Marchfelder (University of Ulm, Germany). Archaea are the third domain of life, alongside eukaryotes and bacteria.
  Discovering new DNA repair enzymes using archaea as a model for mammals
  Dr E Bolt, Dr T Allers
Applications accepted all year round

Funding Type

PhD Type

This PhD research project will combine protein biochemistry and molecular biology methods, and will provide detailed training into how to analyse gene and protein function.
  Mechanisms of cell membranes repair in health and disease
  Dr B Ciani
Applications accepted all year round

Funding Type

PhD Type

Compartmentalisation of chemical reactions and packaging of genetic material is fundamental for the healthy state of any biological cell.
  Activation of targeted DNA Damage Response as a novel therapy for Ovarian Cancer
  Dr E. Sanij, Prof R. Pearson
Applications accepted all year round

Funding Type

PhD Type

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive subtype of ovarian cancer and accounts for 70% of all ovarian cancer deaths.
  Effects of transcription on genome stability
  Prof N J Savery
Applications accepted all year round

Funding Type

PhD Type

Transcription-coupled DNA repair (TCR) pathways prioritise the repair of certain lesions in "active" genes. These pathways help maintain genome integrity throughout the lifetime of multi-cellular organisms, and thus help prevent the occurrence of mutation that might cause cancer or other disorders.
  Chromatin and maintenance of genome stability
  Dr A Chambers
Applications accepted all year round

Funding Type

PhD Type

Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
  Molecular mechanisms of break-induced replication
  Dr S Makovets
Application Deadline: 31 August 2019

Funding Type

PhD Type

Maintenance of genome stability is vital for the survival and propagation of all forms of life. DNA replication threatens genome stability as replication forks often stall, collapse and break.
  Identification and functional characterisation of BRIT1/MCPH1 synthetic lethal genes to treat breast and ovarian cancer
  Dr S Bell, Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Women who have undergone surgery for breast and ovarian cancer often have additional chemotherapy to kill residual cancer cells and prevent recurrence.
  Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis
  Dr D Blažek, Prof Z Zdrahal
Application Deadline: 31 October 2019

Funding Type

PhD Type

Cdk12 is transcriptional cyclin-dependent kinase (Cdk) found mutated in various cancers. In previous studies we found that Cdk12 maintains genome stability via optimal transcription of key homologous recombination repair pathway genes including BRCA1.
  Dynamics of the Structure Maintenance of Chromosome (SMC) complexes
  Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

The SMC (Structure Maintenance of Chromosome) complexes are the key components of higher-order chromatin fibers and play important roles in genome stability.
  Investigation of the Role of Long Non Coding RNA During Skin Development and Wound Healing
  Dr M Ahmed
Applications accepted all year round

Funding Type

PhD Type

Skin morphogenesis occurs under stringent control of epithelial-mesenchymal interactions and result in a formation of the epidermis and a number of different skin appendages (including, the hair follicle, HF).
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round

Funding Type

PhD Type

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
  Repairing DNA Damage in Response to BRAF Mutation
  Dr C McCabe, Prof G Stewart
Applications accepted all year round

Funding Type

PhD Type

We are the leading thyroid cancer research group in the UK; we work on other neoplasias as well, including breast and head and neck etc.
  Integrated mathematical modelling and experimental research into interactions between microorganisms
  Dr J U Kreft
Applications accepted all year round

Funding Type

PhD Type

Our group aims to combine theoretical & experimental approaches to understand major problems in the ecology and evolution of microbes.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Function of miRNAs in formation and regeneration of human hair follicles
  Dr S Kurinna, Dr S Herrick, Prof R Paus
Applications accepted all year round

Funding Type

PhD Type

Recent advances in treating a severe skin condition with autologous transgenic keratinocyte cultures emphasises the importance of molecular mechanisms in selecting subpopulations of skin cells for cutaneous repair [1].
  Reactive Inkjet Printing of Functional Swimmers
  Dr X Zhao
Applications accepted all year round

Funding Type

PhD Type

Production of small-scale devices that can autonomously generate thrust via catalytic reactions within fluidic environments has become an increasingly active field and has led to a focus on potential applications including environmental monitoring and remediation, in vivo drug delivery and repair, and lab on a chip diagnostics.
  PhD Studentship in Biodegradable Polymers: New Directions in Controlled Radical Ring-opening Polymerization
  Dr P Roth
Applications accepted all year round

Funding Type

PhD Type

This project involves the development of novel biodegradable polymers for applications in biomedicine and materials science. Accepted candidates will join the Department of Chemistry at the University of Surrey and work in the Roth research group in the recently renovated Joseph Kenyon laboratory.
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