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We have 19 Biochemistry (signal) PhD Projects, Programmes & Scholarships

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Biochemistry (signal) PhD Projects, Programmes & Scholarships

We have 19 Biochemistry (signal) PhD Projects, Programmes & Scholarships

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Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more
 Supervisors: Dr M Hussain, Dr T Nasim, Prof MR Boyett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The regulation of platelet function - towards new strategies to prevent thrombosis

University of Reading Department of Biomedical Sciences
Project Overview. Platelets perform a pivotal role in the regulation of haemostasis, a physiological response to injury that prevents excessive bleeding. Read more
 Supervisor: Prof J M Gibbins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Advancing Liquid Atmospheric Pressure (LAP) MALDI Mass Spectrometry

University of Reading School of Chemistry & Food
MALDI. mass spectrometry has been a cornerstone of modern biological mass. spectrometry, enabling the soft ionization, analysis and characterisation of. Read more
 Supervisor: Prof R K Cramer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Fully funded PhD studentship: 2D Material enhanced ATR and Raman chips for biomedical sensing applications

University of Southampton Faculty of Engineering and Physical Sciences
Supervisory Team. Prof. Senthil Murugan Ganapathy. Project description. There is an urgent need for diagnostic tools capable of swiftly delivering results directly at patients' bedsides and within doctors' practices. Read more
 Supervisor: Prof S Ganapathy
 Year round applications  PhD Research Project  Competition Funded PhD Project (European/UK Students Only)
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Structural and mechanistic studies of fibroblast growth factor receptor signalling

University of Leeds Faculty of Biological Sciences
The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Prof A.L. Breeze, Prof F. Sobott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Diabetes and Breast Cancer from the perspective of oestrogen receptor expression

Sheffield Hallam University Biomolecular Sciences Research Centre
The Industry and Innovation Research Institute (I2Ri) draws on talents, expertise and facilities across Sheffield Hallam University. Read more
 Supervisors: Dr SA Ahmed, Dr NP Peake, Dr DK Kelly
 10 May 2024  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation

University of Reading School of Pharmacy
Are you ready to delve into the captivating world of molecular signaling and unravel the mysteries of the cardiovascular and nervous systems? We are thrilled to offer an exhilarating PhD opportunity at the forefront of scientific exploration. Read more
 Supervisors: Dr G Cottrell, Prof D Widera, Dr S Amadesi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Urokinase-plasminogen activator as a target to block osteoarthritic cartilage destruction

University of Liverpool Institute of Life Course and Medical Sciences
Osteoarthritis (OA) is one of the major causes of disability globally, which is particularly significant in an ageing population. Read more
 Supervisor: Dr D Wilkinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Is there a Role for Activated Akt in Palatogenesis?

University of Dundee Dental School
Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more
 Supervisors: Dr S. J. Jones, Dr M Islam
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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ERK5 MAPK signalling in Alzheimer’s disease

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
 Supervisors: Dr J Muller, Dr S Kantamneni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Non-canonical functions of SRSF protein kinase (SRPK) in pluripotent stem cells

University of Dundee School of Life Sciences
The overarching goal of our research is to identify and characterise the protein kinase signalling pathways that control stem cell pluripotency and differentiation and determine how protein kinase signalling is disrupted to cause human developmental disorders. Read more
 Supervisor: Dr G Findlay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

University of Dundee School of Life Sciences
Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
 Supervisor: Prof Y Kulathu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel targeted therapeutic approaches through induced-proximity of proteins

University of Dundee School of Life Sciences
Protein post-translational code is at the heart of protein function and signal transduction in cells. Enzymes catalyse the addition or removal of post-translational modifications (PTM), such as phosphorylation, methylation, acetylation, and ubiquitylation, on proteins. Read more
 Supervisors: Prof G Sapkota, Prof A Ciulli
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of P2X7 receptor intracellular domains in cell signalling

Cardiff University Cardiff School of Biosciences
Project description. P2X7 receptors are ion channels that are found on the surface of immune cells, where they respond to the binding of extracellular ATP, a damage signal released by dying cells in infection and injury. Read more
 Supervisors: Dr M Young, Dr J Parker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Plant adaptation to low oxygen conditions

University of Oxford Department of Biology
In plants, cells are exposed to varying oxygen (O. 2. ) concentrations due to changes in environmental availability, metabolic activity, and organ anatomy (Weits et al., 20201; Loreti and Perata, 20202). Read more
 Supervisor: Prof F Licausi
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Taking Light Induced Electron Paramagnetic Resonance In Cell for Biological Structural Determination

The University of Manchester Department of Chemistry
Studying the structure of proteins and other biological systems is an important step in understanding their function. Most structural studies are conducted in environments that are far away from native conditions, such as those found inside a cell. Read more
 Supervisors: Dr A Bowen, Dr J Rowbotham, Dr I Riddell, Dr D Heyes
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Systems level analysis of platelet signalling

University of Reading Department of Biomedical Sciences
We are interested in how intracellular signal transduction networks bring about complex biological behaviours in cells. We do this by combining computational biology with wet laboratory experimentation. Read more
 Supervisors: Dr M J Fry, Prof J M Gibbins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biological role of neuropeptides and their receptors

University of Reading School of Pharmacy
Cell signalling is critical to the co-ordination and functioning of all cells. Cell signalling allows cells to co-ordinate activities within the intracellular environment as well as ensuring cells know how to correctly respond to other cells and to an ever-changing extracellular environment as well. Read more
 Supervisor: Dr L Lander
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways

University of Cambridge Department of Biochemistry
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
 Supervisor: Prof N J Gay
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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