Biochemistry (t cell) PhD Projects, Programmes & Scholarships

Identifying causal pathways to disease using DNA methylation predicted blood traits.

University of Bristol Bristol Medical School

Project Background. Blood cell types have been implicated in pathogenesis of chronic diseases. Genome wide association studies have identified thousands of variants associated with blood trait variation. Read more

Supervisors: Dr J Min, Dr E Hannon, Prof J MIll

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

University of Dundee School of Life Sciences

T lymphocytes mediate long-term adaptive immunity to viruses and tumour cells. T lymphocytes recognize foreign antigens via specific interactions with the T cell receptor (TCR) that is expressed on the cell surface. Read more

Supervisor: Dr T Ly

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

The University of Manchester Faculty of Biology, Medicine and Health

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

Supervisors: Prof D Brough, Dr K Couper

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

University of Greenwich School of Pharmacy (Medway Campus)

Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more

Supervisor: Dr V Sumbayev

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

University of Kent Medway School of Pharmacy

Overview. Immune checkpoint pathways determine the abilities of human malignant tumours to escape cytotoxic immune attack and thus progress the disease. Read more

Supervisor: Dr V Sumbayev

Year round applications PhD Research Project Self-Funded PhD Students Only

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Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

University of Liverpool Institute of Life Course and Medical Sciences

Mesenchymal stem cells (MSCs) are responsible for the repair of damaged tissue following injury and disease as well as moderating innate and adaptive immune responses and regulation of self-tolerance and tissue homeostasis. Read more

Supervisors: Dr R Oldershaw, Dr A Chadwick, Dr M Phelan, Dr BN Norman

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

University of Leicester Molecular and Cell Biology

Whether a cell dies or not has profound consequences on health and disease. In healthy tissue, cells that acquire high levels of genetic damage are safely removed via a process of programmed cell death. Read more

Supervisor: Dr JF Fox

Year round applications PhD Research Project Self-Funded PhD Students Only

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MSc By Research: Research project Exploiting fungal cell wall remodelling mechanisms to combat antifungal drug tolerance

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Prof C Munro, Dr D Childers, Dr H Cao, Dr L Walker

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

King’s College London School of Cancer and Pharmaceutical Sciences

Talented and motivated students, passionate about doing research and advancing cancer research, are invited to apply for this PhD position. Read more

Supervisor: Dr H Sailem

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc by Research: Protein secretion landscapes in human immune cells

University of Dundee School of Life Sciences

Roughly one third of the human genome encodes secretory and membrane proteins. Following synthesis in the endoplasmic reticulum (ER), these proteins are captured into transport vesicles for delivery within the cell. Read more

Supervisors: Dr L Miller, Dr A Howden

Year round applications PhD Research Project Self-Funded PhD Students Only

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Does one size fit all for antimicrobial delivery via nanoparticles

Queen’s University Belfast School of Pharmacy

Antimicrobial resistant bacteria are a growing problem and new ways are needed to target bacterial infections more efficiently. One way in which bacteria can avoid therapeutics is via intracellular infection, where they hide within our own cells. Read more

Supervisors: Dr J Burrows, Prof B Gilmore

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

University of Leicester Molecular and Cell Biology

Nuclear factor-kappa B (NF-kB) is a family of transcription factors that play a crucial role in regulating various cellular processes; primarily related to immune responses, inflammation, and cell survival. Read more

Supervisor: Dr G Hall

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the role and regulation of membraneless granules for the development of T. brucei

University of York York Biomedical Research Institute

Adaptation to a change of environment is an essential process for survival, in particular for parasitic organisms exposed to a wide range of hosts. Read more

Supervisors: Dr M Cayla, Dr P B Walrad

Year round applications PhD Research Project Self-Funded PhD Students Only

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Self-funded PhD- Integrated multi-omics characterisation of human retroviral reservoirs

University of Bristol School of Cellular and Molecular Medicine

Human retroviruses are a group of pathogens infecting an estimated 50 million people worldwide. The most widespread human retrovirus is HIV-1, which remains a major cause of morbidity and mortality, particularly in developing countries. Read more

Supervisor: Dr IL Shytaj

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

University of Leeds Faculty of Biological Sciences

The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisor: Prof I Wood

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating lysosomal (dys)function in ageing and neurodegeneration

University of Reading Department of Biomedical Sciences

Project Overview. Ageing is associated with a decline in the functions of an organism (López-Otín, C. et al. Cell, 2023) and correlates with an increased risk of developing diseases in the later life (Niccoli, T. Read more

Supervisors: Dr S Cogo, Dr E Kevei

Year round applications PhD Research Project Self-Funded PhD Students Only

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Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education

Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more

Supervisor: Dr A Elbediwy

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

University of Dundee School of Life Sciences

During early embryogenesis, segments (somites) are formed during a process called somitogenesis. These somites will go on to form the bones and muscles of the skeleton. Read more

Supervisors: Prof J K Dale, Dr P Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of integrated microfluidic chips for making mRNA nanomedicines

University of Adelaide School of Chemical Engineering

Project. Messenger RNA (mRNA) provides a highly flexible platform for the development of vaccines. A robust immune response typically requires both an antibody response and a T-cell response. Read more

Supervisor: Assoc Prof AS Santos

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!

University of Leicester Molecular and Cell Biology

We're on the lookout for passionate PhD students who are eager to delve deep into the mysteries of our DNA. Our quest? To understand the subtle changes that determine how our genes function, both in sickness and in health. Read more

Supervisor: Dr T Schalch

Year round applications PhD Research Project Self-Funded PhD Students Only

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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more

Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Charting new neuronal survival pathways in Parkinson’s disease

University of Otago Department of Biochemistry

The Neurodegenerative and Lysosomal Disease Laboratory is interested in uncovering the unknown molecular and cellular mechanisms of neurodegenerative diseases, particularly in the development of Parkinson’s disease and Batten disease. Read more

Supervisors: Dr S Hughes, Dr IB Basik

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

University of Birmingham School of Biosciences

Background. To mount an immune response, host organisms must first recognize the pathogen with which they are infected. The first line of defense against pathogen infection in animals is provided through the innate immune response. Read more

Supervisor: Dr M Soller

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Unlocking the Secrets of Genome Regulation through cryo-EM

University of Leicester Molecular and Cell Biology

Are you an ambitious spirit, ready to make breakthrough discoveries at the frontier of epigenetics? Dive deep into the fascinating world of eukaryotic genomes with us! . Read more

Supervisors: Dr T Schalch, Dr AC Chaplin

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

Duchenne muscular dystrophy (DMD) is a severe X-linked genetic disorder affecting 1:5000 boys at birth (1). DMD is caused by mutations in Dystrophin gene, with around 10% of the cases caused by nonsense mutations (2,3). Read more

Supervisors: Dr HZ Zhou, Dr J Meng, Prof F Muntoni

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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PhD Positions in Life Science and Biomedicine Research Groups supported by a structured PhD program

TUD Dresden University of Technology

Paid positions, no tuition fees!. Call opens. 26 February 2024. Call closes. 29 April 2024. Admission panel video interviews for eligible applicants. Read more

Funded PhD Programme (Students Worldwide) Germany PhD Programme

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PhD position in antiviral immunity and vaccinology (m/f/d)

University Hospital of Munich Clinical Pharmacology

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. Read more

Supervisor: Prof S Rothenfusser

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

University of Nottingham School of Medicine

Implanted medical devices are crucial in healthcare, valued at around £400 billion globally, however there is a high failure rate, often due to the foreign body reaction, where a fibrotic capsule forms around the implant with associated inflammation, loosening and infection. Read more

Supervisors: Prof M Alexander, Prof AG Ghaemmaghami, Dr D H Kim, Prof BO Ollivere

30 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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MSc By Research: Unravelling the mechanisms controlling anterior eye development

Aberdeen University School of Medicine, Medical Sciences & Nutrition

The MSc by Research programme at the University of Aberdeen is for students interested in a research-intensive master's degree. It is designed specifically to enhance your skills for a PhD or research career. Read more

Supervisors: Prof L Erskine, Prof N Vargesson

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 31 Biochemistry (t cell) PhD Projects, Programmes & Scholarships

Biochemistry (t cell) PhD Projects, Programmes & Scholarships

We have 31 Biochemistry (t cell) PhD Projects, Programmes & Scholarships

Identifying causal pathways to disease using DNA methylation predicted blood traits.

MSc by Research: Using genome editing to study the mechanisms of immune cell proliferation and differentiation

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

Cross-talks of immune checkpoint pathways determine the abilities of human malignant tumours to suppress cytotoxic attacks and escape immune surveillance

Determining metabolic reprogramming events in stem cells in response to inflammatory disease phenotype

Structural and functional analysis of the protein complexes which regulate cell fate decisions to identify novel cancer therapies

MSc By Research: Research project Exploiting fungal cell wall remodelling mechanisms to combat antifungal drug tolerance

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Evaluating the role of immune microenvironment on cancer progression using spatial and imaging approaches

MSc by Research: Protein secretion landscapes in human immune cells

Does one size fit all for antimicrobial delivery via nanoparticles

Structural and functional characterisation of MALT1 ubiquitination to aid in the development of novel anti-cancer therapies

Investigating the role and regulation of membraneless granules for the development of T. brucei

Self-funded PhD- Integrated multi-omics characterisation of human retroviral reservoirs

Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders

Investigating lysosomal (dys)function in ageing and neurodegeneration

Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

MSc by Research: m6A modification of segmentation clock mRNAs and its role in somitogenesis

Development of integrated microfluidic chips for making mRNA nanomedicines

Join Our Quest to Unravel the Secrets of Eukaryotic Genomes!

A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Charting new neuronal survival pathways in Parkinson’s disease

Analysis of pathogen determinants recognized by the hypervariable immune receptor Dscam

Unlocking the Secrets of Genome Regulation through cryo-EM

Developing an ADAR-mediated RNA editing therapy for treatment of Duchenne Muscular Dystrophy

PhD Positions in Life Science and Biomedicine Research Groups supported by a structured PhD program

PhD position in antiviral immunity and vaccinology (m/f/d)

Elucidating the role of lipids in fibrotic capsule formation at the surface of implanted medical devices.

MSc By Research: Unravelling the mechanisms controlling anterior eye development

We have 31 Biochemistry (t cell) PhD Projects, Programmes & Scholarships

Biochemistry (t cell) PhD Projects, Programmes & Scholarships

We have 31 Biochemistry (t cell) PhD Projects, Programmes & Scholarships

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