Don't miss our weekly PhD newsletter | Sign up now Don't miss our weekly PhD newsletter | Sign up now

We have 12 Biochemistry (yeast) PhD Projects, Programmes & Scholarships

Discipline

Discipline

Biological Sciences

Location

Location

All locations

Institution

Institution

All Institutions

PhD Type

PhD Type

All PhD Types

Funding

Funding

All Funding


Biochemistry (yeast) PhD Projects, Programmes & Scholarships

We have 12 Biochemistry (yeast) PhD Projects, Programmes & Scholarships

Identification of phosphatases that inactivate the endoplasmic reticulum stress sensor Ire1

A self-funded PhD studentship is available in the group of Dr. Martin Schröder in the Department of Biosciences at Durham University to study stress signalling mechanisms originating from the endoplasmic reticulum. Read more

Chaperones and the response to protein misfolding stress

Misfolded proteins are usually refolded to their functional conformations or degraded by quality control mechanisms. When misfolded proteins evade quality control, they form aggregates that are sequestered to specific sites within cells. Read more

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Targeting Ras palmitoylation for the treatment of cancer

Lay summary. Proteins can be thought of as molecular machines that carry out work within cells. Protein activity can be regulated through the reversible attachment of certain chemical groups to specific amino acids within proteins. Read more

Development of a personalized therapy for pulmonary arterial hypertension (PAH)

  Research Group: Pharmacology and Experimental Therapeutics
Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

MSc by Research: Degrade or die: Understanding proteasome regulation upon stress

The Rousseau lab is interested in decoding how protein degradation by the proteasome is regulated in cells so that accumulation of unfolded, misfolded, or damaged proteins can be cleared before they become deleterious. Read more

Understanding gene regulation by HDAC1 complexes in development and cancer

Packaging DNA into nucleosomes helps protect the long fragile genomes of eukaryotic species. However, in doing so it becomes an ever-present physical barrier to the machinery required for its replication, repair and transcription. Read more

Untying the knot: Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways

Open PhD position on Genome Stability and Biochemistry. Joint PhD scholarship - St Andrews and Bonn-Biology. Untying the knot. Remodelling of G4 structures by the NER machinery- implications in human DNA repair and regulatory pathways. Read more

Targeting ageing and neurodegenerative diseases using the fruit-fly Drosophila melanogaster

In the last 20 years the fruit fly Drosophila melanogaster emerged as a pre-eminent model system for studying changes that occur during both normal and pathological ageing (~75 per cent of the genes that cause disease in humans are also found in the fruit fly!). Read more

Investigating monogenic disorders of the protein synthesis machinery

Translation of mRNA into proteins is a critical cellular biological process. We recently described a novel human disorder, now called Faundes-Banka Syndrome (FABAS), caused by heterozygous variants in EIF5A1 that encodes a translation factor. Read more
  • 1

Filtering Results