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Biochemistry (alzheimer) PhD Projects, Programmes & Scholarships
We have 27 Biochemistry (alzheimer) PhD Projects, Programmes & Scholarships
We have 27 Biochemistry (alzheimer) PhD Projects, Programmes & Scholarships
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ERK5 MAPK signalling in Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
Lysozyme encapsulated gold nanoclusters – a new therapeutic agent for Alzheimer’s disease
Alzheimer’s disease (AD) has become a major medical challenge with huge social and economic consequences due to increasing life expectancy. Read more
Generating a disease model for Alzheimer's Disease in non-human primates
Our lab is interested in understanding and treating a devastating neurodegenerative disorder, Alzheimer’s Disease (AD), in particular aspects relating to develop appropriate disease models for AD. Read more
Screening of chemical libraries using iPS models for investigating the role of prion protein in Alzheimer’s disease
Background. AD has been identified as a protein misfolding disease (proteopathy). The disease is caused by accumulation of two major amyloids. Read more
Investigating the timing and causes of vascular dysfunction in Alzheimer’s disease
Rationale. Cerebrovascular damage accelerates and exacerbates cognitive decline and brain damage in Alzheimer's disease (AD)(1, 2). Read more
Neuroinflammation, glial cell dysfunction & neurodegenerative diseases
Neurodegenerative disorders, such as Alzheimer’s disease, are often associated with chronic neuroinflammation and glial cell dysfunction that acts to exacerbate neuronal damage and loss of synapses. Read more
PhD Studentship - A multi-model approach to investigate the role of early neuroinflammation in dementia with Lewy bodies
Overview. Dementia with Lewy bodies (DLB) is a common form of dementia caused by the abnormal folding and aggregation of the synaptic protein alpha-synuclein. Read more
Characterisation of the neuronal receptor for soluble amyloid precursor protein: a route to new therapeutic targets for Alzheimers disease
Alzheimer’s disease (AD) is the commonest form of dementia for which currently there is no means of stopping or even slowing the disease. Read more
BBSRC MIBTP - Identification of pathways deregulating neuronal ELAV/Hu RNA binding proteins and alternative splicing in neurodegeneration
Research Group:
BBSRC MIBTP
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions. Read more
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Native Mass Spectrometry for the Structural Elucidation of Protein Machines
Research Group:
BBSRC MIBTP
Native mass spectrometry is an expanding structural biology tool that is being used to elucidate the structure of protein complexes and their functions within cells. Read more
Protein degradation-based gene therapies for neurodegenerative disease
Proteins fold like origami into complex three-dimensional shapes. This process can malfunction and result in misfolded proteins that stick together to form large aggregates. Read more
Platelets in health, ageing and disease: new diagnostics and treatments
Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders
Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more
Cell growth signalling in space: How does mTOR kinase communicate with diverse cellular compartments?
PROJECT IN BRIEF. This 4-year PhD project addresses the fundamental question of how individual cells sense and respond to environmental changes. Read more
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