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Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships

We have 102 Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships

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We have 102 Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships

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Regulation of nuclear actin in human cancer

Actin is a cytoskeletal protein that plays essential roles in many cellular processes, such as adhesion, intracellular trafficking, membrane dynamics and motility. Read more

Novel non-coding RNAs in regulating cancer epigenome

This opportunity will remain open until a suitable candidate has been found and so early applications are encouraged. Cancer-associated changes in gene expression and genome stability are often attributed to variations in DNA methylation. Read more
Last chance to apply

Shaping the actin cortex of cells by Curly, a newly found actin bending protein

This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. For further details. Read more

Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens

Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine. Read more

Control and inhibition of virus replication

The Tuplin laboratory utilises a range of cutting-edge approaches to investigate how arboviruses - specifically Chikungunya, Dengue and Zika viruses - control replication and translation of their genomes through interactions between RNA structures, host cell proteins and non-coding RNA, and the potential of such RNA elements/interactions as novel therapeutic targets. Read more

Understanding cellular receptors mediating signalling and viral infection - molecular mechanisms and development of new therapeutics

Cellular receptors initiate signalling pathways that regulate all aspects of cell behaviour and these receptors are key therapeutic targets for a wide range of diseases including cardiovascular disease and cancer. Read more

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more

Face off – Dissecting the role of phase separation in viral replication and antiviral responses

Background. The assembly of membraneless organelles is emerging as a fundamental paradigm for many cellular functions. Among these, stress granules (SGs) play a central role in health and disease by concentrating proteins and RNAs, driving adaption to stressful conditions, including viral infection. Read more

MSc by Research: Bringing proteins together with functional small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a game-changing new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more

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