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Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships
We have 103 Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships
We have 103 Biochemistry (cellular biology) PhD Projects, Programmes & Scholarships
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MSc by Research: Mechanisms underlying aphid effector virulence activity
Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more
Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more
Characterization of the molecular mechanisms of breast cancer metastasis to bone: from basic research to biomarkers
About the Project. Breast cancer is responsible for over 300,000 cancer diagnoses within the UK per annum, and it is estimated that one in 7 women will develop breast cancer. Read more
ERK5 MAPK signalling in Alzheimer’s disease
Research Group:
Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
Multisystem functional characterisation of the ciliopathy disease candidate gene DNAAF9 (aka Shulin)
Motile cilia are vital cellular structures which move in a whip-like manner to propel cells (ex. Sperm cells) or move fluids over tissue surfaces (ex. Read more
Does membrane repair fail to alert the immune system to disease?
The cGAMP-synthase cGAS recognises microbial or self-DNA to activate STING and induce the release of pro-inflammatory molecules. But cytoplasmic DNA is also particularly abundant in cancer cells, under the form of genomic structures called ‘micronuclei’. Read more
Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
Mechanisms of cell membranes repair in health and disease
Compartmentalisation of chemical reactions and packaging of genetic material is fundamental for the healthy state of any biological cell. Read more
Involvement of P2X7 receptors in cancer
The P2X receptors are a family of ligand-gated receptor channels activated by ATP and other extracellular nucleotides. A member of this family, the P2X7 purinergic receptor has been shown to play a crucial role in various physiological and pathophysiological processes. Read more
EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture
Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more
Small G proteins and their effectors as therapeutic targets in cancer
For the majority of cancers the acquisition of invasive and metastatic characteristics leads to incurable disease in the host. Read more
Ubiquitin signals in Parkinson’s disease
Ubiquitin signalling controls almost every cellular process in humans, including targeting poorly folded proteins for destruction to prevent them harming the cell. Read more
Bioinformatics studies of protein structures, functions and their interactions
The computational study of protein structures, functions and their interactions is fundamental to our understanding of disease. Read more