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We have 489 Biochemistry PhD Projects, Programmes & Scholarships

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Biochemistry PhD Projects, Programmes & Scholarships

We have 489 Biochemistry PhD Projects, Programmes & Scholarships

A PhD in Biochemistry would provide you with the time and resources to undertake an in-depth research project into one area of biochemistry. These projects are almost always laboratory-based and can range from investigating the structure and role of a protein or receptor to developing and optimising current detection methods.

What’s it like to do a PhD in Biochemistry?

Doing a PhD in Biochemistry, you’ll develop wide-spread laboratory skills including protein purification, western blotting, chromatography, and polymerase chain reaction (PCR). The use of cutting-edge equipment such as nuclear magnetic resonance (NMR) is common in Biochemistry and consequently you’ll become proficient with these fine instruments.

Some typical research topics in Biochemistry include:

  • Engineering enzymes for industry
  • Characterising the structure and function of proteins
  • Developing novel therapeutics
  • Understanding the role of redox in a system or disease
  • Investigation of a specific receptor
  • Developing and optimising methods (such as NMR)

Day-to-day you’ll be in the laboratory performing experiments, writing up and analysing data from previous experiments and discussing your results and research plans with colleagues.

Biochemistry programmes are almost always advertised research projects, with the key aim pre-determined by the supervisor. Although the aim is set, you are still free to influence the direction of the project along the way. These advertised programmes usually come with full funding attached.

It is uncommon to propose your own research in Biochemistry as you must find a supervisor with research goals that overlap with your project, who also has adequate equipment for your experimental work, and you must find sufficient funding for bench and PhD fees.

Regardless of being funded or not, your PhD will end with a thesis of around 60,000 words, which contributes significantly to the knowledge of the field. To be awarded your PhD, you’ll then need to defend your thesis during your viva exam.

Entry requirements

The entry requirements for most Biochemistry PhD programmes involve a Masters in a subject directly related to Biochemistry such as Biology or Chemistry, with at least a Merit or Distinction. If English isn’t your first language, you’ll also need to show that you have the right level of language proficiency.

PhD in Biochemistry funding options

The Research Council responsible for funding Biochemistry PhDs in the UK is the Biotechnology and Biological Sciences Research Council (BBSRC). They provide fully-funded studentships including a stipend for living costs, a consumables budget for bench fees and a tuition fee waiver. Students don’t apply directly to the BBSRC, you apply for advertised projects with this funding attached.

It’s uncommon for Biochemistry PhD students to be ‘self-funded’ due to the additional bench fees. However, if you were planning to fund yourself it might be achievable (depending on your project) through the UK government’s PhD loan and part-time work.

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Understanding control of genome folding by cohesin

Our basic goal is to understand how chromatin structure influences gene regulation. Chromatin is generally repressive in nature but its structure is manipulated by cells in a regulated way to determine which genes are potentially transcriptionally active and which genes remain repressed in a given cell type. Read more

Chemical energy conversion in biology studied using advanced spectroscopic and structural tools

Redox properties of metal-containing active sites are critically important to many biocatalytic processes. one third of all proteins contain a redox-active metal, and ca 22% of submissions to the Protein Data Bank contain a transition metal. Read more

Self-funded PhD- Re-engineering Golgi dynamics in plants – investigating the role of myosin receptors

The growing global population requires the development of novel strategies to sustainably increase food production. Organelle movement is dynamic and linked to changes in cell size, plant biomass and in response to factors which affect food production such as pathogens (Perico and Sparkes, New Phytol. Read more

Linking metabolism and metal resistance in pathogenic bacteria (SULLIVANM_U24AMSSCI)

Primary supervisor - Dr Matthew Sullivan. Group B Streptococcus (GBS) is an effective pathogen of humans and animals and is well known as the leading cause of often-fatal infections in newborn infants. Read more

Self-funded MSc R- Re-engineering Golgi dynamics in plants – investigating the role of myosin receptors

The growing global population requires the development of novel strategies to sustainably increase food production. Organelle movement is dynamic and linked to changes in cell size, plant biomass and in response to factors which affect food production such as pathogens (Perico and Sparkes, New Phytol. Read more

Natural products in bacterial physiology and chemical interaction

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Obtaining insights into how a signalling hub protein Ras activates multiple effectors

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. They are highly conserved from yeast to humans, highlighting their fundamental biological roles. Read more

Molecular level understanding of Mycobacterium tuberculosis

Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more

Structural-guided PROTAC targeting of BMX to modulate apoptotic sensitivity in disease

What determines at the molecular level whether a cell lives or dies? Regulation of the cellular life–death switch is essential in healthy cells for normal foetal development and for the clearance of damaged cells. Read more

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

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