Sequenced genomes of mycobacteria, including the human tuberculosis causing pathogen Mycobacterium tuberculosis, reveal a number of genes dedicated to lipid biosynthesis and transport. Read more
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017). Read more
Necrosis, a form of premature cell death, is frequently caused by excessive insults such as trauma, infection and toxins. It has been implicated in many human diseases including cancer, neurodegenerative disorders and inflammatory diseases. Read more
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions. Read more
Apicomplexan parasites are widespread protozoan parasites of animals. The phylum Apicomplexa contains thousands of species and includes major pathogens of humans, domestic animals and livestock. Read more
The Preston lab (www.prestonlab.com) at RCSI is seeking to recruit 2 x PhD students to join an SFI-funded research programme studying molecular pathways at the interface of blood coagulation and innate immunity. Read more
TO APPLY, CLICK 'INSTITUTION WEBSITE'. Infant leukaemia is an aggressive malignancy with cure rates of less than 50%. Importantly, despite large international trials, there has been no improvement in survival over the last 2 decades. Read more
TO APPLY CLICK 'INSTITUTION WEBSITE' . The genetic landscape of mesothelioma is dominated by loss of function mutations in various tumour suppressor genes (eg. Read more
TO APPLY CLICK 'INSTITUTION WEBSITE' . Recent years have seen a revolution in our ability to generate high-resolution microscopic images of tumour tissue to reveal gene activity in single cells. Read more
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