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University of Birmingham, Institute of Cancer and Genomic Sciences Biochemistry PhD Projects, Programs & Scholarships

We have 6 University of Birmingham, Institute of Cancer and Genomic Sciences Biochemistry PhD Projects, Programs & Scholarships

  • Biochemistry×
  • University of Birmingham
  • Institute of Cancer and Genomic Sciences×
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  Investigating the regulation of DNA replication by ubiquitylation
  Dr A Gambus
Applications accepted all year round

Funding Type

PhD Type

Every dividing cell needs to duplicate its genome perfectly before cell division. Failure to do so can result in cell death or development of mutations leading to cancer.
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round

Funding Type

PhD Type

Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
  Regulation of autophagy in human embryonic stem cells and its therapeutic application in induced pluripotent stem cell-based disease models
  Dr S Sarkar
Applications accepted all year round

Funding Type

PhD Type

Project background. Regulation of proteostasis is critical for maintaining tissue homeostasis. Autophagy, a major intracellular degradation pathway essential for cellular and energy homeostasis, functions in the clearance of aggregation-prone proteins and damaged organelles.
  The importance of the DNA damage response in neurodegeneration
  Dr R Tuxworth
Applications accepted all year round

Funding Type

PhD Type

DNA damage occurs in early-stage neurodegenerative diseases. The response of neurons to the damage may contribute to disease progression by inducing senescence, cell-cycle and apoptosis.
  The Role of LIM Domain Only Proteins in Neuroblastoma
  Dr M Hoogenkamp
Applications accepted all year round

Funding Type

PhD Type

Person Specification. An Upper Second Class Honours Degree (or equivalent) in a relevant study or Master’s degree is expected. Prior experience in cell and molecular biology is an advantage.
  Transcription regulation in the context of genome stability
  Dr M Saponaro
Applications accepted all year round

Funding Type

PhD Type

The DNA in our cells is a substrate for both RNA Pol II (RNAPII) transcription and DNA replication. Consequently, only one of the two processes can use the DNA as a template at any given time.
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