Biochemistry (fibrosis) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 11 Biochemistry (fibrosis) PhD Projects, Programmes & Scholarships for Self-funded Students

MSc by Research: Molecular characterisation of the factors driving lung fibrosis

University of Dundee School of Life Sciences

Idiopathic pulmonary fibrosis (IPF) is a progressive disease that results in an irreversible decline in lung function. At present IPF is normally fatal and the median survival is between 2 and 5 years after diagnosis. Read more

Supervisors: Prof S Arthur, Dr H McSorley

Year round applications PhD Research Project Self-Funded PhD Students Only

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Preclinical testing of collagen synthesis inhibitors for fibrotic disease

University of Liverpool Institute of Ageing and Chronic Disease Department of Musculoskeletal Biology

Fibrotic disease is characterised by an excessive accumulation of collagen within tissues, which then impedes tissue function. Organ fibrosis specifically kidney fibrosis, liver fibrosis, cardiac fibrosis and lung fibrosis have limited treatment options, pose a huge clinical burden and are life-limiting diseases. Read more

Supervisor: Dr EG Laird

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the Therapeutic Potential of Cannabidiol (CBD) in Cardiac Fibrosis

University of Reading School of Pharmacy

Cardiac fibrosis is a condition that is characterized by the abnormal accumulation of fibrous tissue within the heart muscle and poses a significant threat to cardiovascular health. Read more

Supervisors: Dr G Cottrell, Prof D Widera

31 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Investigation of novel protease-antiprotease imbalances associated with cystic fibrosis and the effect of CFTR correction.

Queen’s University Belfast School of Pharmacy

Cystic fibrosis (CF) is a progressive life-limiting airways disease that affects over 162,000 people worldwide. Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Selective targeting of furin for the treatment of fibrotic lung disease.

Queen’s University Belfast School of Pharmacy

Furin, a proprotein convertase has been established as a therapeutic target across several disease areas to include chronic airways diseases and infectious disease, such as COVID-19 (reviewed in our recent publication, Douglas et al, 2023). Read more

Supervisor: Prof L Martin

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical: Gastroesophageal reflux in respiratory disease: pathogenic role and improved management

University of Leeds Faculty of Medicine and Health

Gastroesophageal reflux disease (GERD) is a condition in which stomach contents, such as food and acid pass into the gullet/oesophagus causing heartburn. GERD is very common in patients with lung disease, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). Read more

Supervisors: Prof L Houghton, Dr D Peckham

Year round applications PhD Research Project Self-Funded PhD Students Only

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Leveraging novel automated diagnostic pathways with augmented precision medicine approaches for the early detection and risk stratification of liver disease

University of Dundee School of Medicine

Liver disease represents one of the fastest-growing causes of morbidity and mortality in the world. The principle aetiological variants are contained within the new nomenclature of steatotic liver disease (SLD). Read more

Supervisors: Dr P Brennan, Prof J F Dillon, Dr M Al-Khairalla

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Investigating the impact of galectin-ligand interaction on cancer cell resistance to chemotherapeutic treatment

University of Liverpool Institute of Life Course and Medical Sciences

Galectins are multifunctional carbohydrate-binding proteins that are expressed by many types of human cells. Changes of galectin expression commonly occur in cancer (e.g. Read more

Supervisor: Prof LG Yu

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of a personalized therapy for pulmonary arterial hypertension (PAH)

University of Bradford Faculty of Life Sciences

Research Group: Pharmacology and Experimental Therapeutics

Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder which, if left untreated, leads to heart failure and death. Read more

Supervisor: Dr T Nasim

Year round applications PhD Research Project Self-Funded PhD Students Only

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Targeting senescence to ameliorate ageing and treat cancer and other age-related diseases

University of Leicester Molecular and Cell Biology

Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more

Supervisor: Prof S Macip

Year round applications PhD Research Project Self-Funded PhD Students Only

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Regulation of virulence and biofilm formation by quorum sensing and the "stress alarmone" ppGpp in gram-negative pathogenic bacteria.

University of Cambridge Department of Biochemistry

We are investigating the complex interplay between cell-cell signalling (quorum sensing), microbial lifestyle (i.e., free-living planktonic cultures vs sessile biofilm communities), growth phase and virulence in gram-negative bacteria. Read more

Supervisor: Dr M Welch

Year round applications PhD Research Project Awaiting Funding Decision/Possible External Funding

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We have 11 Biochemistry (fibrosis) PhD Projects, Programmes & Scholarships for Self-funded Students

Biochemistry (fibrosis) PhD Projects, Programmes & Scholarships for Self-funded Students

We have 11 Biochemistry (fibrosis) PhD Projects, Programmes & Scholarships for Self-funded Students

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