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Biochemistry PhD Projects, Programmes & Scholarships

We have 477 Biochemistry PhD Projects, Programmes & Scholarships



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We have 477 Biochemistry PhD Projects, Programmes & Scholarships

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3 PhD positions avaliable within the DFG-funded Clinical Research Unit PhenoTImE (CRU 337-2)

 The University Hospital Essen offers first class medical services in the Ruhr metropolis. Every year,. 225.000 patients are treated in 30 clinics, 27 institutes and specialized centers. Read more

Exploring the Molecular Mechanism of Novel Mitochondrial Neurotoxins identified through a Machine Learning Approach

Mitochondrial inhibition is an important ‘OFF-target’ mechanism of drug-induced toxicity in the clinic, contributing to drug attrition in clinical trials and drug withdrawal following approval because of severe adverse events 1. Read more

Identifying novel regulators of haematopoiesis using flies

Supervisors. Iwan Evans (primary supervisor); Steve Brown (Biosciences, secondary supervisor). Project details. Control of blood cell proliferation, survival and activation is critical to the health of an organism. Read more

Meals for macrophages – investigating how macrophages engulf and process dying cells in vivo

Supervisors. Iwan Evans (primary supervisor); Phil Elks and Simon Johnston (secondary supervisors). Project details. A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Read more

Investigating the control and function of macrophage subtypes using Drosophila melanogaster

Supervisor(s). Iwan Evans (Primary Supervisor, IICD) and Martin Zeidler (Second Supervisor, Biosciences). Project details. The phagocytic white blood cells known as macrophages are a highly heterogeneous population of cells. Read more

Noise-induced transitions in gene regulatory networks

Our world is full of noise sources at different spatial and temporal scales. The temperature and sunlight changes day to night. A receptor protein interacts with its target molecule undergoing Brownian motion. Read more

Disruption of nuclear envelope regulation of miRNA, enhancer, and gene loci positioning leads to aberrant development and disease

  Research Group: Institute of Cell Biology
Defects in spatial genome organisation are linked to human disease and it is speculated that most as yet unidentified disease alleles will occur in non-coding genome regions. Read more

Expanding the ligandable E3 ubiquitin ligases for targeted protein degradation

Out of more than 600 E3 ubiquitin ligases in cells, currently only a handful have small molecule binders that can be used for PROteolysis Targeting Chimeras (PROTACs) and harnessed for targeted protein degradation. Read more

Regulation and mechanics in polarity

Membranes and their protein organization are a frontier in our understanding of cell biology. We focus on polarized trafficking as a model to uncover fundamental mechanisms in the organization of structures at membranes. Read more

Is there a Role for Activated Akt in Palatogenesis?

Main Aim. The project will use a medial edge epithelial (MEE) cell line as an in vitro model. These cells will be used to investigate the effects of exogenous TGFβ-3 and activation of Akt on cell migration, epithelial to mesenchymal transition (EMT) and apoptosis. Read more

Studying novel histone acylations in the regulation of gene expression

Title of the project. Studying novel histone acylations in the regulation of gene expression. Project summary. In the nucleus of eukaryotes, DNA wraps around octamers of histone proteins to form a structure called chromatin. Read more

Investigating the effects of host-pathobiont interactions on inflammation resolution in chronic inflammatory disease

Host-microbiota homeostasis is pertinent for the maintenance of a healthy state. Chronic inflammatory diseases, which are often linked, such as rheumatoid arthritis (RA) or cardiovascular disease, are characterised by disturbances on both sides. Read more

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