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Biochemistry (cell therapy) PhD Projects, Programmes & Scholarships

We have 33 Biochemistry (cell therapy) PhD Projects, Programmes & Scholarships

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We have 33 Biochemistry (cell therapy) PhD Projects, Programmes & Scholarships

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EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

Epigenetic regulation of cholangiocarcinoma growth

Cholangiocarcinoma (CCA) is a rare malignant bile duct tumour with an average incidence of 1/100,000 in the population per year. The overall incidence of CAA includes 15% of primary liver cancers, the second most common type of primary liver cancer. Read more

Synthetic transition metal catalysts for the treatment of cancer

Working the interfaces of chemical catalysis, analytical chemistry, cellular biology, pharmacology and medicine, this project provides unique interdisciplinary training in the skills required for the development of a pre-clinical metal-based therapy. Read more

Exploiting metabolic vulnerabilities induced by dietary restriction as novel therapies for infant leukaemia

TO APPLY, CLICK 'INSTITUTION WEBSITE'. Infant leukaemia is an aggressive malignancy with cure rates of less than 50%. Importantly, despite large international trials, there has been no improvement in survival over the last 2 decades. Read more

Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more

Can the natural health supplement Fisetin reverse senescence in vascular cells?

Cellular senescence is a mechanism that is activated in stressed cells to prevent the replication of damaged DNA. Senescent cells are found in vessel walls as well as in other tissues and have been shown to play a role in ageing and age-related diseases such as cardiovascular disease. Read more

Investigating the utility of exercise to enhance the yield of haemopoietic stem and progenitor cells in peripheral blood

Haemopoietic stem and progenitor cells (HSPC’s) are donated by approximately 2000 healthy individuals for patients with a variety of blood cancers and genetic disorders in the UK every year, however; there are barriers that limit this process working optimally. Read more

Platelets in health, ageing and disease: new diagnostics and treatments

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more

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