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We have 42 The University of Manchester Biochemistry PhD Projects, Programmes & Scholarships

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Biological Sciences

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The University of Manchester

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The University of Manchester Biochemistry PhD Projects, Programmes & Scholarships

We have 42 The University of Manchester Biochemistry PhD Projects, Programmes & Scholarships

(MRC DTP CASE) Understanding how tumour associated macrophages control the tumour immune landscape in NF2-Schwannomatosis

Type 2 Neurofibromatosis (NF2), now referred to as NF2-Schwannomatosis (or NF2-SWN), is a rare autosomal dominant tumour pre-disposition syndrome characterised by growth of typically benign tumours throughout the nervous system. Read more

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

How does the dynamic intra-membrane aggregation of phage lysis proteins kill bacterial pathogens?

This is an interdisciplinary project. It will provide a unique opportunity to obtain training in a wide range of interdisciplinary skills, including protein engineering techniques, protein purification, atomic force microscopy, neutron reflection and scattering as well as molecular dynamics simulations. Read more

Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

Alternative Materials and Processes for the Textile and Fashion Industry

The fashion and textile industries conduct some of the most polluting practices on the planet. Many initiatives are striving to positively impact the issues the industry faces, in line with climate targets and UN sustainable development goals. Read more

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