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University of Manchester Biochemistry PhD Projects, Programs & Scholarships

We have 125 University of Manchester Biochemistry PhD Projects, Programs & Scholarships

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  EPSRC Centre for Doctoral Training in the Science and Applications of Graphene and Related Nanomaterials (Graphene-NOWNANO)
University of Manchester & Lancaster University, North West Nanoscience Doctoral Training Centre. Graphene NOWNANO is a recently established Centre for Doctoral Training (CDT) at the University of Manchester in partnership with Lancaster University.
  (A*STAR) Analysis of the role of microRNAs in the regulation of NF-kappaB dynamics and function
  Prof M White, Dr A P Gilmore
Application Deadline: 31 January 2019
The project will investigate the control of NF-kB. This transcription factor is one of most important cell signalling systems in the body that controls inflammation and cell fate.
  (A*STAR) Elucidating the role of polyamines in the epidermal skin barrier
  Dr S Cruickshank, Dr K Mace, Dr A Saunders
Application Deadline: 31 January 2019
Delayed wound healing is a major health issue affecting one in 50 people. The process of wound healing is a highly orchestrated process involving many cell types and regulatory networks.
  (A*STAR) Engineering of virus-like particles and novel multimeric assemblies as scaffolds for presentation of viral antigens
  Prof J P Derrick, Dr F Hayes
Application Deadline: 31 January 2019
This project will use structural vaccinology to investigate the potential for de novo engineering of large, synthetic macromolecular assemblies.
  (A*STAR) Investigating the role of Lrg1 in chronic kidney diseases
  Dr S Abraham, Prof M Tomaszewski, Dr N Ashton
Application Deadline: 31 January 2019
Chronic Kidney Disease (CKD) affects 10-20% of adults and is a major and increasing public health burden. CKD has several aetiologies that share a final common pathway characterised by an inadequate angiogenic response to renal hypoxia that could potentially serve to enhance the fibrotic phenotype.
  (A*STAR) Programming human pancreatic progenitors for endocrine differentiation
  Prof N Hanley, Dr R Jennings
Application Deadline: 31 January 2019
There is an exciting opportunity for a PhD student to undertake highly distinctive, interdisciplinary research on human pancreatic beta cell differentiation.
  (A*STAR) Structure-based ligand discovery targeting protein kinases for antifungal therapy
  Dr L Tabernero, Dr M Bromley
Application Deadline: 31 January 2019
Fungal infections pose a serious threat to health affecting about 1.7 billion people worldwide and causing about 1.5 million deaths each year.
  (BBSCR DTP) Design of allosteric small molecule probes of fibrosis using molecular dynamics simulations
  Dr R A Bryce, Dr K Piper Hanley, Dr R Whitehead
Application Deadline: 31 January 2019
Integrins are a family of protein receptors that play a major role in cell survival, growth and migration. Their function is to transmit signals across the cell membrane by undergoing an elegant large scale structural rearrangement.
  (BBSRC DTP CASE) Anti-inflammatory microbes and their potential as topical therapeutics
  Prof C A O'Neill, Prof A McBain
Application Deadline: 31 January 2019
The epidermis of skin is the primary interface between the body and the outside world. As such, the epidermis is constantly under threat of dehydration as there is a permanent driving force for water to leave the skin to the external dry environment.
  (BBSRC DTP CASE) Applying – omics methods to map the circadian matrisome
  Dr J Swift, Dr Q-J Meng, Prof K E Kadler
Application Deadline: 31 January 2019
Circadian rhythm regulates and synchronises biological processes through a daily cycle. Molecular clocks in cells throughout the human body are entrained to a ‘master clock’ located in the hypothalamus, and cells in almost all tissues have been found to contain rhythmic genes.
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