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Bioinformatics (flow cytometry) PhD Projects, Programs & Scholarships

We have 17 Bioinformatics (flow cytometry) PhD Projects, Programs & Scholarships

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Showing 1 to 10 of 17
  Characterising B cells in Rheumatoid Arthritis: Their role in susceptibility, pathogenesis, and treatment response
  Dr S Viatte, Dr Gemma Radley, Prof A Barton
Applications accepted all year round

Funding Type

PhD Type

Background. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects the joints. In the UK, some patients who fail to respond to methotrexate (MTX) and TNF inhibitors (TNFi) are started on rituximab, and 20% will experience a favourable clinical response.
  Immune phenotyping of refractory rheumatoid arthritis disease
  Prof Maya Buch, Dr S Viatte
Applications accepted all year round

Funding Type

PhD Type

Treatment of rheumatoid arthritis (RA) has been transformed with the introduction of targeted therapies twenty years ago (comprising biologic disease modifying anti-rheumatic drugs, bDMARDS; and the more recent small molecule JAK inhibitors).
  Exploring the transcriptomic and chromatin landscapes of fibroblast-like synoviocytes in rheumatoid arthritis
  Dr S Eyre, Mr P Martin, Dr AM Morris
Applications accepted all year round

Funding Type

PhD Type

Genetic studies in rheumatoid arthritis (RA) have been successful in identifying regions of the genome which contribute to disease risk, but it is often unclear which genes they effect.
  The molecular mechanisms of thrombosis and haemostasis
  Dr C.E. Hughes
Applications accepted all year round

Funding Type

PhD Type

A healthy cardiovascular system relies on the cells lining the blood vessels (endothelial cells) and heart cells (cardiomyocytes) to function normally.
  ExomiR resetting of the energy profile in Hepatocellular Cancer (HCC) via the mitochondrial proteome
  Prof N Heaton, Dr S E Khorsandi
Application Deadline: 30 April 2020

Funding Type

PhD Type

Project description. The issue/problem. Hepatocellular cancer (HCC) is a primary liver cancer and one of the commonest cancers in the world.
  Micro-environmental Interactions And Non-Coding RNAs In The Biology Of B Cell Leukemia
  Prof M Mráz
Application Deadline: 20 February 2020

Funding Type

PhD Type

We are looking for motivated PhD students for a project funded by the prestigious ERC (European Research Council) Grant (laboratory of Assoc.
  Using computational and imaging approaches to uncover mechanisms of spatial organisation
  Dr S Murray
Application Deadline: 15 March 2020

Funding Type

PhD Type

We are currently looking for a PhD student to work on the development of a framework for gaining mechanistic insight into spatial sub-cellular processes.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Combining Synthetic Biology and Modelling to Understand and Predict Evolution
  Dr M Lagator, Dr J-M Schwartz
Applications accepted all year round

Funding Type

PhD Type

Mutations, and their effects on organismal fitness, lie at the heart of understanding and predicting evolution. Because of its central role in determining evolutionary outcomes, much experimental and theoretical effort has been put into describing the fitness effects of mutations.
  Predicting treatment response in juvenile idiopathic arthritis using a single cell genomics based approach
  Prof W Thomson, Dr S Smith, Mr P Martin, Prof A Morris
Applications accepted all year round

Funding Type

PhD Type

Background. Juvenile idiopathic arthritis (JIA) is a group of chronic arthropathies of unknown cause which can result in long-term disability and poor quality of life for children and can continue well into adult life.
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