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Bioinformatics (genes) PhD Projects, Programs & Scholarships

We have 57 Bioinformatics (genes) PhD Projects, Programs & Scholarships

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  Genomics, gene regulation and disease: how mammalian genes are regulated and how their deregulation is linked with human disease
  Assoc Prof J Hughes, Prof T Milne
Application Deadline: 26 July 2019

Funding Type

PhD Type

The Hughes group is interested in how mammalian genes are regulated and how their deregulation is linked with human disease. The ~22 thousand genes in the mammalian genome are present in the DNA of every cell but are used in complex patterns in different cell types and organs.
  Genetic Epidemiology of Cardiovascular Disease: Studying genetic variation in cardiomyopathy and coronary artery disease across the entire allele frequency spectrum in order to identify causative genes and susceptibility loci.
  Prof M Farrall, Dr AG Goel
Application Deadline: 26 July 2019

Funding Type

PhD Type

Studying genetic variation in cardiomyopathy and coronary artery disease across the entire allele frequency spectrum in order to identify causative genes and susceptibility loci.
  Using canine models of obesity to discover the mechanisms by which genes influence obesity.
  Dr E Raffan, Dr D Sargan
Applications accepted all year round

Funding Type

PhD Type

We are interested in discovering the mechanisms by which genes influence obesity. The dog is an excellent model organism for human comparative analyses.
  The physiological roles of the Rasd1 interactome in the central control of hydromineral homeostasis
  Prof D Murphy, Dr M Greenwood
Applications accepted all year round

Funding Type

PhD Type

The brain mechanisms responsible for osmotic stability are located in the hypothalamo-neurohypophyseal system (HNS), which consists of magnocellular neurons located in the supraoptic nucleus (SON) and paraventicular nucleus (PVN), the axons of which terminate in the posterior pituitary gland.
  How human teeth form and how that process fails in the inherited condition amelogenesis imperfecta
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Amelogenesis is the process of enamel formation and is essential for the development of functional teeth. Amelogenesis imperfecta (AI) is a failure of that process.
  Identifying the genetic determinants of translation rate in blood cells and characterising their relevance to human traits
  Dr E Turro, Dr W Astle, Dr M Frontini
Application Deadline: 31 May 2019

Funding Type

PhD Type

The central dogma of molecular biology states that genetically encoded information flows from DNA to mRNA to protein. The flow from DNA to mRNA occurs through a process called transcription and the flow from mRNA to protein through a process called translation.
  Genome and transcriptome sequencing and functional analysis to find new mutation types in patients with inherited blindness
  Prof C Inglehearn
Applications accepted all year round

Funding Type

PhD Type

Human inherited retinal dystrophies (IRDs) result from mutations in over 200 different genes, many of them first implicated by the Leeds Vision Research Group (eg Panagiotou E et al 2017, AJHG 100:960-968; El-Asrag M et al 2015, 96:948-54).
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Moonlight activities for cyclin genes in plants (MOUBAYIDINJ18RS)
  Dr L Moubayidin
Application Deadline: 28 May 2019

Funding Type

PhD Type

The control of cell division in plant development is crucial to achieve coherent organ patterning, and bilateral and radial symmetry.
  Clinical Genetics: De Novo Mutations, Selfish Selection, Mosaicism and Human Disease - developing methods for identification of new genes/molecular pathways subject to selfish selection within the human testis
  Prof A Goriely, Prof A Wilkie
Application Deadline: 26 July 2019

Funding Type

PhD Type

De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most of them originate, the human testis.
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