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We have 131 Bioinformatics (it) PhD Projects, Programmes & Scholarships

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Bioinformatics (it) PhD Projects, Programmes & Scholarships

We have 131 Bioinformatics (it) PhD Projects, Programmes & Scholarships

Multilevel selection on transposition rates in cancer

Cancer is an evolutionary process. Cells in a tumour vary due to mutation, and so over many generations they adapt in response to both intrinsic selective pressures (such as anoxia) and extrinsic selective pressures (such as chemotherapy). Read more

Epigenetics and Cancer: Determining how Mistakes in V(D)J Recombination Trigger Leukaemias and Lymphomas

V(D)J recombination is essential to produce an effective adaptive immune system but since the reaction involves breakage and rejoining of DNA, it is highly dangerous and errors have long been thought to lead to leukaemias and lymphomas. Read more

Molecular mechanisms of pacemaker (sinus node) dysfunction in ageing, heart failure and athletes

  Research Group: Chemistry and Biosciences
The heart’s pacemaker, the sinus node, initiates the action potential that causes the heart to beat, and the atrioventricular node conducts the action potential from the atria to the ventricles, the pumping chambers of the heart. Read more

Data-driven optimal prediction of bacteria growth

This project is devoted to an AI-based prediction of bacteria growth and its control by antibiotics. In synthetic biology, an improved understanding of bacterial regulatory circuits is required to develop complex biological systems with functionalities beyond existing in nature [1, 2]. Read more

Construction and attentional control of complex thought and behaviour

  Research Group: Centre for Mind and Behaviour
Research Group. Centre for Mind and Behaviour. Proposed supervisory team. Prof Peter Bright (Psychology). Dr Mike Pake. Dr Ian van der Linde (Computing & Information Science). Read more

In silico modelling of endocannabinoid evolution

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Developing synthetic microbial communities for the control of pea downy mildew

Demand for food production is increasing due to growing global population, reduced land availability for agriculture, concern over the effects of the environment on agriculture, and decreasing yield reliability because of climate change. Read more

Exploring Viral Nucleic Acid Machinery via Cryo Electron Microscopy to Advance Biomedicine

Viruses, these tiny but potent life forms, are all around us, infecting various organisms and directly affecting human health. Although in most cases, viral infection is not life threatening, in the minority of cases it leads to long-term disorders including cancer. Read more

Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more

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