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"maternal" AND "health"×
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Bioinformatics (maternal health) PhD Projects, Programs & Scholarships

We have 9 Bioinformatics (maternal health) PhD Projects, Programs & Scholarships

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  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  (MRC DTP) Peri-conceptional stress signalling through O-GlcNAcylation: effects on the early maternal-embryonic interface
  Prof J Aplin, Prof M Westwood, Dr Peter Ruane, Dr A Stevens
Application Deadline: 15 November 2019

Funding Type

PhD Type

Cellular stress during the peri-conceptional period, including that caused by assisted reproductive treatment (ART), can lead to early pregnancy loss, reduced gestation or birthweight and altered postnatal growth, with short- (neurodevelopmental delay) and long- (cardiovascular and metabolic disease)-term health consequences.
  Using Statistical Techniques in Genetic Epidemiology to Investigate the Developmental Origins of Health and Disease (DOHaD)
  Prof D Evans
Applications accepted all year round

Funding Type

PhD Type

There is a well-documented observational relationship between low birthweight infants and increased risk of disease in later life (e.g.
  (MRC DTP) Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Application Deadline: 15 November 2019

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Phenotyping placental disease in women with diabetes and chronic hypertension using transcriptomic analysis
  Dr J Myers, Dr E Johnstone
Applications accepted all year round

Funding Type

PhD Type

Placental disease triggers medically-indicated preterm birth in 1 in 6 pregnancies complicated by chronic hypertension and/or diabetes (cardiometabolic disease).
  (BBSRC DTP) Understanding the contribution of dietary extracellular vesicles to healthy human development
  Prof M Westwood, Dr L Harris, Prof A Nicolaou, Dr A Stevens
Application Deadline: 31 January 2020

Funding Type

PhD Type

The ability to adapt behaviour in response to nutrient availability is important for all cells but particularly so for trophoblasts, as these cells form the placenta - the interface between mother and fetus - and act as fetal sentinels of the maternal environment.
  What can big data tell us about outcomes of epilepsy?
  Research Group: Centre for Clinical Brain Sciences
  Dr R Chin, Dr C Weir, Dr SB Bhattacharya
Application Deadline: 6 January 2020

Funding Type

PhD Type

With a diagnosis of epilepsy comes questions about health, educational and social outcomes. For women there are specific questions about pregnancy outcomes.
  (MRC DTP) Placental vascular development in pregnancies complicated by diabetes
  Dr J Myers, Dr E Johnstone, Dr P Brownbill, Dr I Chernyaysky
Application Deadline: 15 November 2019

Funding Type

PhD Type

Maternal diabetes (type 1 & 2) complicates 2-3% of pregnancies. Abnormal fetal growth is common in these pregnancies, manifest as both fetal overgrowth (macrosomia) and fetal growth restriction.
  Precision Medicine DTP - Blood flow and solute transport in human placental vascular networks: an in-silico approach to characterising pregnancy pathologies
  Dr T Krueger, Dr M Bernabeu
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. The human placenta performs diverse functions later taken on by several different organs. In particular, it mediates the exchange of vital solutes, including respiratory gases and nutrients, between the mother and the developing fetus.
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