Bioinformatics (molecular modelling) PhD Projects, Programmes & Scholarships

We have 23 Bioinformatics (molecular modelling) PhD Projects, Programmes & Scholarships

Machine Learning and Molecular Modelling in Mass Spectrometry

University of Leeds Faculty of Biological Sciences

This PhD project will harness the power of computational modelling and machine learning (A.I.) to analyse data obtained by mass spectrometry experiments and predict structural characteristics of biomolecules and their interactions. Read more

Supervisors: Prof F. Sobott, Dr A Kalli, Dr H Wang

Year round applications PhD Research Project Self-Funded PhD Students Only

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Predicting drug solubility in different solvents using molecular simulation and machine learning

University of Strathclyde Department of Chemical and Process Engineering

Predicting the solubility of complex drug-like molecules is crucial at several stages of the drug discovery and manufacture. In particular, solvent selection has been highlighted as a crucial step in process design and optimisation [1]. Read more

Supervisors: Dr M Jorge, Prof C Price

Year round applications PhD Research Project Self-Funded PhD Students Only

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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more

Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn

1 May 2024 PhD Research Project Self-Funded PhD Students Only

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Personalising cancer treatment with tumour evolution modelling using AI-based genomics biomarkers and PK/PD

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Tumour heterogeneity is a major problem limiting the efficacy of targeted oncological therapies. Most advanced tumours eventually become resistant to the treatments, ultimately making the patient succumb to metastatic disease. Read more

Supervisor: Dr T You

1 August 2024 PhD Research Project Self-Funded PhD Students Only

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Network-based predictive modelling of cardiovascular disease risk

University of Liverpool Institute of Systems, Molecular and Integrative Biology

The risk of cardiovascular disease (CVD) is orchestrated by multiple factors. QRISK models (currently QRISK3) have been used in the UK to estimate CVD risk within the next 10 years for individuals without CVD. Read more

Supervisor: Dr T You

Year round applications PhD Research Project Self-Funded PhD Students Only

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PhD in stem cell modelling for neuropsychiatric disorders

University of Melbourne Anatomy and Physiology

This project provides a unique opportunity to explore the developmental origins of schizophrenia—a severe mental health disorder—using cutting-edge patient-derived stem cell models. Read more

Supervisor: Dr M Di Biase

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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New Methods for modelling cofactor-dependent enzyme structure and function

The University of Manchester Department of Chemistry

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Supervisor: Prof S Hay

27 October 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Genetics of flowering shoot temperature responses in plants

Durham University Department of Biosciences

The shape of plants is shaped by both genetics and environment; changes in response to temperature can be the most dramatic of all. Read more

Supervisor: Dr J Hepworth

3 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Using genome engineering and bioinformatics to understand heterochromatin and centromere function in Schizosaccharomyces pombe and in cancer cells

University of Nottingham School of Life Sciences

Centromeres are the DNA sequences on eukaryotic chromosomes that mediate accurate chromosome segregation at both mitotic and meiotic cell divisions. Read more

Supervisors: Dr W R A Brown, Dr W Wickstead

Year round applications PhD Research Project Self-Funded PhD Students Only

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New methods for modelling radionuclide binding proteins

The University of Manchester Department of Chemistry

The management of radioactively contaminated land and water is a multi-billion pound, 100+ year grand challenge that requires innovation to minimise costs. Read more

Supervisors: Prof S Hay, Dr L Natrajan

Year round applications PhD Research Project Competition Funded PhD Project (UK Students Only)

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In silico modelling of endocannabinoid evolution

University of Worcester Research School

In the brain, the endocannabinoid (eCB) system maintains adequate neurotransmission (Lu and Mackie 2016). Indeed, the eCB system provides a negative feedback mechanism, preventing over-activation of synaptic transmission. Read more

Supervisor: Dr M Di Micelli

Year round applications PhD Research Project Self-Funded PhD Students Only

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Systems immunology and multi-omics approaches to understand protective immunity to human malaria

University of Queensland Institute for Molecular Bioscience

This PhD project aims to develop and apply computational approaches that integrate systems biology and molecular immunology to understand host-pathogen immunity and predict immune control of malaria. Read more

Supervisor: Prof D Doolan

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Where has all of the carbon gone? Understanding the molecular mechanisms of long-term soil carbon capture

The University of Manchester Department of Earth and Environmental Sciences

Soils, while unglamorous, form the basis of the terrestrial biosphere and are ultimately the source of the majority of the food that we eat, yet fundamental aspects of how soils form and how they store carbon are poorly understood. Read more

Supervisors: Prof D Cameron, Dr S Nixon

Year round applications PhD Research Project Funded PhD Project (UK Students Only)

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Genetics: Investigating the molecular basis of optic nerve degeneration in glaucoma to try and develop a personalized medicine strategy for treatment

University of Leeds Faculty of Medicine and Health

The optic nerve is a special sensory nerve that transmits visual impulses from the retina to the brain. Primary Open Angle Glaucoma (POAG) is a chronic, progressive optic neuropathy of multifactorial origin that affects 1 in 10 elderly individuals. Read more

Supervisor: Dr M Ali

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 23 Bioinformatics (molecular modelling) PhD Projects, Programmes & Scholarships

Bioinformatics (molecular modelling) PhD Projects, Programmes & Scholarships

We have 23 Bioinformatics (molecular modelling) PhD Projects, Programmes & Scholarships

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