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We have 12 Bioinformatics (protein engineering) PhD Projects, Programmes & Scholarships

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Bioinformatics (protein engineering) PhD Projects, Programmes & Scholarships

We have 12 Bioinformatics (protein engineering) PhD Projects, Programmes & Scholarships

Protein engineering enzymes for Industry

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

Identification and characterisation of bacteriocins from environmental samples active against strains of Clostridium difficile.

Clostridiodes difficile is a cause of neonatal enteritis in livestock such as pigs, cattle and horses. Affected animals develop respiratory problems, abdominal distention and bloody diarrhoea leading to weight loss and in extreme cases mortality. Read more

Glycosylation in Microalgal Host Cells

Microalgae have generated increasing interest as microbial cell factories to produce therapeutics proteins. This is because they can grow on very cheap media and their GRAS (generally regarded as safe) status means they are a fantastic option for the production of therapeutics that can be administered orally. Read more

New Methods for modelling cofactor-dependent enzyme structure and function

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more
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