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Bioinformatics (repair) PhD Projects, Programs & Scholarships

We have 7 Bioinformatics (repair) PhD Projects, Programs & Scholarships

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  Harnessing inflammation to repair extracellular-matrix rich tissues
  Dr M Sherratt, Dr G Lopez-Castejon, Dr C Platt
Applications accepted all year round

Funding Type

PhD Type

Inflammation is thought to play a key role in mediating many aspects of both age and disease. The aberrant expression of tissue proteases is a hallmark of inflammation.
  Promoting tissue repair with natural cell-signalling peptides
  Dr M Sherratt, Dr A P Gilmore, Dr M Ozols
Applications accepted all year round

Funding Type

PhD Type

In many tissues damage to the extracellular matrix (ECM) can accumulate over a lifetime resulting in the functional manifestations of skin ageing and diseases such as arteriosclerosis, emphysema and arthritis.
  Chromatin remodelling in health and disease: determining the role of ATRX in the maintenance of chromatin and how mutations perturb disparate nuclear nuclear processes and lead to human disease
  Dr R Gibbons, Prof D Higgs
Application Deadline: 26 July 2019

Funding Type

PhD Type

It has become apparent that the regulation of chromatin structure is of paramount importance in a wide variety of fundamental nuclear processes including gene expression, DNA replication, repair and recombination.
  Understanding the role of cohesin and the impact of structural variation on gene expression regulation in the 3D genome
  Prof N J Gooderham, Dr R David
Application Deadline: 31 July 2019

Funding Type

PhD Type

The genome has a three-dimensional (3D) configuration and is interconnected with nuclear architecture, both of which are critical for gene regulation and cell functionality in normal physiology and disease.
  Dynamics of the Structure Maintenance of Chromosome (SMC) complexes
  Prof J Palecek
Application Deadline: 31 October 2019

Funding Type

PhD Type

The SMC (Structure Maintenance of Chromosome) complexes are the key components of higher-order chromatin fibers and play important roles in genome stability.
  Characterization and functional analysis of a novel cancer-associated gene
  Dr JP de Magalhaes
Applications accepted all year round

Funding Type

PhD Type

In order to identify new candidate cancer-related genes, our lab developed a bioinformatics “guilt-by-association” method to identify and rank genes that are co-expressed with known cancer-related genes.
  Integrative Computational Biology and Machine Learning: Combining computational biology, computational chemistry, and machine learning techniques with biological big data to unravel the higher genomic code of life
  Dr A Sahakyan, Prof P McHugh
Application Deadline: 26 July 2019

Funding Type

PhD Type

In the Sahakyan Group, we strive to make computational biology maximally independent from empirical experimental data, by basing our models and predictions on genomic sequences and core biological mechanisms.
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