University of Edinburgh Featured PhD Programmes
University of Warwick Featured PhD Programmes
Birkbeck, University of London Featured PhD Programmes
University of Dundee Featured PhD Programmes
University of Reading Featured PhD Programmes
"transcription"×
10 miles

Bioinformatics (transcription) PhD Projects, Programs & Scholarships

We have 50 Bioinformatics (transcription) PhD Projects, Programs & Scholarships

  • "transcription" ×
  • Bioinformatics×
  • clear all
Order by 
Showing 1 to 10 of 50
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round

Funding Type

PhD Type

MMP13 (collagenase 3) plays a vital role in the pathogenesis of osteoarthritis (OA) because MMP13 preferentially cleaves type II collagen, the main component of cartilage, and both MMP13 levels and enzymatic activity are enhanced in OA.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round

Funding Type

PhD Type

The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  Biochemical analysis of the interaction of pluripotency transcription factors with RNA polymerase enzymes
  Research Group: Institute of Stem Cell Research
  Prof I Chambers
Application Deadline: 5 January 2020

Funding Type

PhD Type

Pluripotent stem cells possess the dual defining properties of self-renewal and multi-lineage differentiation potential. To retain an effective differentiation capacity, self-renewal must occur at high efficiency.
  Stopping transcription at the end of mammalian protein coding genes: How is this achieved and why does this matter
  Prof N J Proudfoot
Application Deadline: 10 January 2020

Funding Type

PhD Type

This research project will focus on my lab’s recent development of genomic methodology for nascent transcription analysis (1).
  Evolution of gene regulatory networks after gene duplication
  Research Group: Lymphocyte Development
  Prof M Merkenschlager, Dr P Sarkies
Application Deadline: 1 December 2019

Funding Type

PhD Type

Throughout evolution multicellular organisms have experienced large-scale structural alterations, in which regions of the genome or even the entire genome have been duplicated (1-7).
  Precision Medicine DTP - The role of transcription factors and the signaling environment in commitment of cells into the germline
  Research Group: Institute of Stem Cell Research
  Prof I Chambers, Dr T Chandra
Application Deadline: 8 January 2020

Funding Type

PhD Type

Background. In mammals, specification of the germline occurs shortly after implantation. Understanding how germ cells become specified is important both to inform the treatment of human infertility, for example through in-vitro spermatogenesis, and for the wider field of regenerative medicine.
  The role of cyclin-dependent kinases (CDKs) in transcription and cell cycle control.
  Prof C Norbury, Prof S Murphy
Application Deadline: 10 January 2020

Funding Type

PhD Type

Cyclin-dependent kinases (CDKs), including CDK1, 2, 4 and 6, act as master regulators of the cell cycle through phosphorylation of numerous protein targets (1).
  Understanding the gene regulatory landscape of embryonic stem cells and cancer cells
  Prof A Sharrocks, Prof M Rattray
Applications accepted all year round

Funding Type

PhD Type

Cell identity is ultimately determined through decoding the genome through the action of gene regulatory mechanisms. In particular, sculpting of the chromatin landscape to reveal unique configurations of gene regulatory elements in each cell type is a major driver of cell identity.
  New ways of terminating transcription in bacterial pathogens
  Dr C Brown
Applications accepted all year round

Funding Type

PhD Type

An excellent PhD candidate (’A’ grades) interested in researching the fundamental process of gene expression in bacteria is being recruited to join a multidisciplinary team led at University of Otago, Dunedin, New Zealand.
  Understanding the role that the RNA helicase UPF1 plays in sorting ribonucleoprotein (RNP) complexes and the mechanism by which this role of UPF1 might reduce cellular stress and cell degeneration.
  Research Group: BBSRC MIBTP
  Dr S Brogna
Application Deadline: 7 January 2020

Funding Type

PhD Type

This project’s specific objective is to study the molecular role(s) that the RNA helicase UPF1 plays in RNA processing. UPF1 is a key player in nonsense-mediated mRNA decay (NMD), it is universally conserved in eukaryotes and is essential to the development of many organisms [1].
Show 10 15 30 per page


FindAPhD. Copyright 2005-2019
All rights reserved.